1H-Pyrrole-1-aceticacid,2-(aminomethyl)-alpha-methyl-,(S)-(9CI)

Base Information

Chemical Name:1H-Pyrrole-1-aceticacid,2-(aminomethyl)-alpha-methyl-,(S)-(9CI)
CAS No.:145041-25-4
Molecular Formula:C₈H₁₂N₂O₂
Molecular Weight:168.195
Hs Code.:
Mol file:145041-25-4.mol

Synonyms:1H-Pyrrole-1-aceticacid, 2-(aminomethyl)-a-methyl-, (S)- (9CI)

Suppliers and Price of 1H-Pyrrole-1-aceticacid,2-(aminomethyl)-alpha-methyl-,(S)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1H-Pyrrole-1-aceticacid,2-(aminomethyl)-alpha-methyl-,(S)-(9CI)

Chemical Property:

Boiling Point:341.5±27.0 °C(Predicted)
PKA:2.65±0.10(Predicted)
PSA：68.25000
Density:1.25±0.1 g/cm3(Predicted)
LogP:1.29270

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Pyrrole-1-aceticacid,2-(aminomethyl)-alpha-methyl-,(S)-(9CI)

There total 3 articles about 1H-Pyrrole-1-aceticacid,2-(aminomethyl)-alpha-methyl-,(S)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 60026-30-4,145041-24-3
(2S)-2-(2-formyl-1H-pyrrol-1-yl)propionic acid

: 145041-25-4
(S)-2-(2-Aminomethyl-pyrrol-1-yl)-propionic acid

Guidance literature:: With ammonium acetate; sodium cyanoborohydride; In methanol; for 18h; Ambient temperature;
DOI:10.1016/0040-4039(92)89043-C

Reference yield:

: 116763-06-5
(-)-(S)-methyl 2-pyrrol-1-ylpropanoate

: 145041-25-4
(S)-2-(2-Aminomethyl-pyrrol-1-yl)-propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: TiCl₄ / CH₂Cl₂ / 1.5 h / -40 °C

2: NaOH / methanol; H₂O / 18 h / Heating

3: 67 percent / NaCNBH₃, NH₄OAc / methanol / 18 h / Ambient temperature

With sodium hydroxide; ammonium acetate; titanium tetrachloride; sodium cyanoborohydride; In methanol; dichloromethane; water;
DOI:10.1016/0040-4039(92)89043-C

Reference yield:

: 145041-23-2
(S)-methyl 2-(2-formyl-1H-pyrrol-1-yl)propanoate

: 145041-25-4
(S)-2-(2-Aminomethyl-pyrrol-1-yl)-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / methanol; H₂O / 18 h / Heating

2: 67 percent / NaCNBH₃, NH₄OAc / methanol / 18 h / Ambient temperature

With sodium hydroxide; ammonium acetate; sodium cyanoborohydride; In methanol; water;
DOI:10.1016/0040-4039(92)89043-C