4-ETHYNYL-2-FLUORO-1-METHYL-BENZENE

Base Information

Chemical Name:4-ETHYNYL-2-FLUORO-1-METHYL-BENZENE
CAS No.:145069-53-0
Molecular Formula:C9H7 F
Molecular Weight:134.1502832
Hs Code.:2903999090
Mol file:145069-53-0.mol

Synonyms:4-ETHYNYL-2-FLUORO-1-METHYL-BENZENE;Benzene, 4-ethynyl-2-fluoro-1-methyl- (9CI)

Suppliers and Price of 4-ETHYNYL-2-FLUORO-1-METHYL-BENZENE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-Ethynyl-2-fluoro-1-methylbenzene 95.00
2.500g
$ 1733.00

American Custom Chemicals Corporation
4-ETHYNYL-2-FLUORO-1-METHYL-BENZENE 95.00%
5MG
$ 503.77

A1 Biochem Labs
4-Ethynyl-2-fluoro-1-methylbenzene 95%
2.5 g
$ 1050.00

Total 9 raw suppliers

Chemical Property of 4-ETHYNYL-2-FLUORO-1-METHYL-BENZENE

Chemical Property:

Vapor Pressure:2.14mmHg at 25°C
Refractive Index:1.511
Boiling Point:168.4°C at 760 mmHg
Flash Point:46.9°C
PSA：0.00000
Density:1.04g/cm³
LogP:2.11540

Purity/Quality:

97% ^*data from raw suppliers

4-Ethynyl-2-fluoro-1-methylbenzene 95.00 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-ETHYNYL-2-FLUORO-1-METHYL-BENZENE

There total 5 articles about 4-ETHYNYL-2-FLUORO-1-METHYL-BENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51436-99-8
2-fluoro-4-bromotoluene

: 1066-54-2
trimethylsilylacetylene

: 145069-53-0
3-Fluoro-4-methylphenylacetylene

Guidance literature:: With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; triphenylphosphine; In toluene; for 12h; Reflux; Inert atmosphere;

Reference yield:

: trimethyl-[2-(3-fluoro-4-methylphenyl)ethynyl]silane

: 145069-53-0
3-Fluoro-4-methylphenylacetylene

Guidance literature:: With potassium carbonate; In methanol; at 20 ℃; for 2h;
DOI:10.1021/jm030327l

Reference yield:

: 39998-81-7
2-fluoro-4-iodotoluene

: 145069-53-0
3-Fluoro-4-methylphenylacetylene

Guidance literature:: Multi-step reaction with 2 steps

1: (PPh₃)2PdCl₂; CuI; Et₃N / 18 h / 20 °C

2: aq. K₂CO₃ / methanol / 2 h / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium carbonate; triethylamine; In methanol;
DOI:10.1021/jm030327l