5''-O-(DIMETHOXYTRITYL)-S6-(2,4-DINITROPHENYL)-N2-PHENYLACETYL-2''-DEOXYTHIOGUANOSINE

Base Information

Chemical Name:5''-O-(DIMETHOXYTRITYL)-S6-(2,4-DINITROPHENYL)-N2-PHENYLACETYL-2''-DEOXYTHIOGUANOSINE
CAS No.:141076-17-7
Molecular Formula:C₄₅H₃₉N₇O₁₀S
Molecular Weight:869.912
Hs Code.:
Mol file:141076-17-7.mol

Synonyms:5''-O-(DIMETHOXYTRITYL)-S6-(2,4-DINITROPHENYL)-N2-PHENYLACETYL-2''-DEOXYTHIOGUANOSINE

Suppliers and Price of 5''-O-(DIMETHOXYTRITYL)-S6-(2,4-DINITROPHENYL)-N2-PHENYLACETYL-2''-DEOXYTHIOGUANOSINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 5''-O-(DIMETHOXYTRITYL)-S6-(2,4-DINITROPHENYL)-N2-PHENYLACETYL-2''-DEOXYTHIOGUANOSINE

Chemical Property:

PSA：246.79000
LogP:8.76880

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5''-O-(DIMETHOXYTRITYL)-S6-(2,4-DINITROPHENYL)-N2-PHENYLACETYL-2''-DEOXYTHIOGUANOSINE

There total 6 articles about 5''-O-(DIMETHOXYTRITYL)-S6-(2,4-DINITROPHENYL)-N2-PHENYLACETYL-2''-DEOXYTHIOGUANOSINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 869355-10-2
N²-phenylacetyl-2'-deoxy-6-thioguanosine

: 141076-17-7
N-[9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-(2,4-dinitro-phenylsulfanyl)-9H-purin-2-yl]-2-phenyl-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / acetonitrile

2: pyridine

With pyridine; triethylamine; In acetonitrile;
DOI:10.1016/S0040-4020(01)88731-7

Reference yield:

: 99519-11-6
3',5'-diacetyl-N²-phenylacetyl-2'-deoxyguanosine

: 141076-17-7
N-[9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-(2,4-dinitro-phenylsulfanyl)-9H-purin-2-yl]-2-phenyl-acetamide

Guidance literature:: Multi-step reaction with 6 steps

1: Et₃N, 4-(dimethylamino)pyridine / CH₂Cl₂ / 1 h / Ambient temperature

2: CH₂Cl₂ / 1) ice-bath, 30 min, 2) RT, 30 min.

3: thiolacetic acid / CH₂Cl₂ / 1 h

4: 2M NaOH

5: Et₃N / acetonitrile

6: pyridine

With pyridine; dmap; sodium hydroxide; triethylamine; tiolacetic acid; In dichloromethane; acetonitrile;
DOI:10.1016/S0040-4020(01)88731-7

Reference yield:

: 141076-15-5
3',5'-diacetyl-N²-phenylacetyl-2'-deoxy-6-thioguanosine

: 141076-17-7
N-[9-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-(2,4-dinitro-phenylsulfanyl)-9H-purin-2-yl]-2-phenyl-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 2M NaOH

2: Et₃N / acetonitrile

3: pyridine

With pyridine; sodium hydroxide; triethylamine; In acetonitrile;
DOI:10.1016/S0040-4020(01)88731-7