Technology Process of 2-Acetyl-butanoic-d5 Acid Ethyl Ester
There total 1 articles about 2-Acetyl-butanoic-d5 Acid Ethyl Ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium carbonate;
at 20 ℃;
for 41h;
DOI:10.1002/jlcr.1235
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: 95 percent / ZnI2 / CH2Cl2 / 16 h / 20 °C
2.1: dibenzyl-dicarbonate; NaBH4 / NiCl2*6H2O / methanol / 17 h / 20 °C
3.1: H2 / Pd/C / ethanol
3.2: 20 °C / high vacuum
4.1: 95 percent / H2SO4 / 24 h / 20 °C
5.1: toluene / 9 h / 110 °C
6.1: 72 percent / MeOH / 20 °C
With
methanol; sodium tetrahydroborate; sulfuric acid; hydrogen; zinc(II) iodide;
palladium on activated charcoal; nickel dichloride;
In
methanol; ethanol; dichloromethane; toluene;
DOI:10.1002/jlcr.1235
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 95 percent / ZnI2 / CH2Cl2 / 16 h / 20 °C
2.1: dibenzyl-dicarbonate; NaBH4 / NiCl2*6H2O / methanol / 17 h / 20 °C
3.1: H2 / Pd/C / ethanol
3.2: 20 °C / high vacuum
4.1: 95 percent / H2SO4 / 24 h / 20 °C
5.1: toluene / 9 h / 110 °C
6.1: 72 percent / MeOH / 20 °C
7.1: 85 percent / DMAP; NEt3 / CH2Cl2 / 20 °C
With
methanol; dmap; sodium tetrahydroborate; sulfuric acid; hydrogen; triethylamine; zinc(II) iodide;
palladium on activated charcoal; nickel dichloride;
In
methanol; ethanol; dichloromethane; toluene;
DOI:10.1002/jlcr.1235
