2-Azabicyclo[2.2.1]heptan-6-ol,acetate(ester),(1S-exo)-(9CI)

Base Information

Chemical Name:2-Azabicyclo[2.2.1]heptan-6-ol,acetate(ester),(1S-exo)-(9CI)
CAS No.:145374-99-8
Molecular Formula:C₈H₁₃NO₂
Molecular Weight:155.197
Hs Code.:
Mol file:145374-99-8.mol

Synonyms:2-Azabicyclo[2.2.1]heptan-6-ol,acetate(ester),(1S-exo)-(9CI)

Suppliers and Price of 2-Azabicyclo[2.2.1]heptan-6-ol,acetate(ester),(1S-exo)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Azabicyclo[2.2.1]heptan-6-ol,acetate(ester),(1S-exo)-(9CI)

Chemical Property:

PSA：38.33000
LogP:0.62870

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Azabicyclo[2.2.1]heptan-6-ol,acetate(ester),(1S-exo)-(9CI)

There total 3 articles about 2-Azabicyclo[2.2.1]heptan-6-ol,acetate(ester),(1S-exo)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 140927-01-1
Acetic acid (1R,4S,6R)-2-benzyl-2-aza-bicyclo[2.2.1]hept-6-yl ester

: 145295-10-9,145374-99-8
Acetic acid (1R,4S,6R)-(2-aza-bicyclo[2.2.1]hept-6-yl) ester

Guidance literature:: With ammonium formate; palladium on activated charcoal; In methanol; for 1h; Yield given; Heating;
DOI:10.1021/jm00090a006

Reference yield:

: 112375-05-0,150851-98-2
N-benzyl-2-azanorborn-5-ene

: 145295-10-9,145374-99-8
Acetic acid (1R,4S,6R)-(2-aza-bicyclo[2.2.1]hept-6-yl) ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) 1M BH₃*THF, 2.) NaOH, 50percent H₂O₂ / 1.) THF, 0-10 deg C, 2 h, 2.) THF, H₂O, 35-40 deg C, 1.5 h

2: 90 percent / Et₃N, DMAP / CH₂Cl₂ / Ambient temperature

3: HCO₂NH₄ / Pd/C / methanol / 1 h / Heating

With dmap; sodium hydroxide; borane-THF; dihydrogen peroxide; ammonium formate; triethylamine; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/jm00090a006

Reference yield:

: 46407-10-7
exo-2-benzyl-2-azabicyclo<2.2.1>heptan-6-ol

: 145295-10-9,145374-99-8
Acetic acid (1R,4S,6R)-(2-aza-bicyclo[2.2.1]hept-6-yl) ester

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / Et₃N, DMAP / CH₂Cl₂ / Ambient temperature

2: HCO₂NH₄ / Pd/C / methanol / 1 h / Heating

With dmap; ammonium formate; triethylamine; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/jm00090a006