16-Acetylandrosta-4,16-dien-3-one

Base Information

Chemical Name:16-Acetylandrosta-4,16-dien-3-one
CAS No.:14508-12-4
Molecular Formula:C21H28 O2
Molecular Weight:312.452
Hs Code.:
European Community (EC) Number:238-516-5
Nikkaji Number:J241.275F
Mol file:14508-12-4.mol

Synonyms:14508-12-4;16-Acetylandrosta-4,16-dien-3-one;(8S,9S,10R,13S,14S)-16-acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthren-3-one;NS00053796

Suppliers and Price of 16-Acetylandrosta-4,16-dien-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 16-Acetylandrosta-4,16-dien-3-one

Chemical Property:

Vapor Pressure:1.11E-08mmHg at 25°C
Boiling Point:461°Cat760mmHg
Flash Point:171.5°C
PSA：34.14000
Density:1.1g/cm³
LogP:4.64360
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:312.208930132
Heavy Atom Count:23
Complexity:640

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC2(CCC3C(C2C1)CCC4=CC(=O)CCC34C)C
Isomeric SMILES:CC(=O)C1=C[C@]2(CC[C@H]3[C@H]([C@@H]2C1)CCC4=CC(=O)CC[C@]34C)C

Technology Process of 16-Acetylandrosta-4,16-dien-3-one

There total 8 articles about 16-Acetylandrosta-4,16-dien-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (3S,8S,9S,10R,13S,14S)-16-(1-Hydroxy-ethyl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

: 14508-12-4
16-acetylandrosta-4,16-dien-3-one

Guidance literature:: With cyclohexanone; aluminum isopropoxide; In toluene; Heating;

Reference yield:

: 53-43-0
dehydroepiandrosterone

: 14508-12-4
16-acetylandrosta-4,16-dien-3-one

Guidance literature:: Multi-step reaction with 6 steps

1: NaH

2: CsF

3: NaBH₄ / methanol

4: aq. HCl

5: 230 mg / diethyl ether

6: 180 mg / Al(O-iPr)3; cyclohexanone / toluene / Heating

With hydrogenchloride; sodium tetrahydroborate; cyclohexanone; aluminum isopropoxide; sodium hydride; cesium fluoride; In methanol; diethyl ether; toluene; 6: Oppenauer oxidation;

Reference yield:

: 20797-16-4
16-formyl-3β-hydroxyandrosta-5,16-diene

: 14508-12-4
16-acetylandrosta-4,16-dien-3-one

Guidance literature:: Multi-step reaction with 2 steps

1: 230 mg / diethyl ether

2: 180 mg / Al(O-iPr)3; cyclohexanone / toluene / Heating

With cyclohexanone; aluminum isopropoxide; In diethyl ether; toluene; 2: Oppenauer oxidation;