(2S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonyl(15N)amino]butanoic acid

Base Information

Chemical Name:(2S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonyl(15N)amino]butanoic acid
CAS No.:141509-91-3
Molecular Formula:C10H19 N O4
Molecular Weight:218.27
Hs Code.:
DSSTox Substance ID:DTXSID70583870
Mol file:141509-91-3.mol

Synonyms:141509-91-3;(2S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonyl(15N)amino]butanoic acid;N-(tert-Butoxycarbonyl)-L-(~15~N)valine;DTXSID70583870;Boc-Val-OH-15N, 98 atom % 15N

Suppliers and Price of (2S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonyl(15N)amino]butanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (2S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonyl(15N)amino]butanoic acid

Chemical Property:

Melting Point:77-80 °C(lit.)
PSA：75.63000
LogP:2.01120
Storage Temp.:-15°C
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:218.12844298
Heavy Atom Count:15
Complexity:242

Purity/Quality:: 98% by CP; 98% atom 15N ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)O)NC(=O)OC(C)(C)C
Isomeric SMILES:CC(C)[C@@H](C(=O)O)[15NH]C(=O)OC(C)(C)C

Technology Process of (2S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonyl(15N)amino]butanoic acid

There total 1 articles about (2S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonyl(15N)amino]butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 59935-29-4,71261-62-6,96817-46-8
(S)-⁽¹⁵⁾N-2-amino-3-methyl butanoic acid

: 24424-99-5
di-tert-butyl dicarbonate

: 141509-91-3
(15N)-N^α-t-Boc-L-valine

Guidance literature:: With sodium hydroxide; at 0 ℃;
DOI:10.1039/c1ob06278f

Reference yield: 77.0%

: 1738-68-7
Gly-OBz

: 141509-91-3
(15N)-N^α-t-Boc-L-valine

: 141509-92-4
C₁₉H₂₈N⁽¹⁵⁾NO₅

Guidance literature:: With isobutyl chloroformate;

Reference yield: 3.0%

: 15761-39-4,59433-50-0
1-(tert-butoxycarbonyl)-L-proline

: 13734-41-3
t-Boc-L-valine

: 13139-15-6,53296-34-7
N-tert-butoxycarbonyl-L-leucine

: 7536-55-2
N-tert-butyloxycarbonylasparagine

: 7536-58-5,98482-77-0
BOC-L-aspartic acid 4-benzyl ester

: 13726-85-7
Boc-Gln-OH

: 13574-13-5
Boc-Glu(OBzl)-OH

: 120267-95-0
Boc-Arg(Z)2-OH

: 18942-46-6,58290-35-0
N-(tert-butyloxycarbonyl)-S-(4-methoxybenzyl)cysteine

: C₂₄H₂₉N₂O₆Pol

: 54613-99-9
Boc-(S)-Lys(2-Cl-Z)-OH

: 47355-10-2
Nα-tert-butoxycarbonyl-1-formyl-L-tryptophan

: 139952-87-7
[15N]-N-(tert-butoxycarbonyl)-L-alanine

: 141509-91-3
(15N)-N^α-t-Boc-L-valine

: C₁₄H₁₉⁽¹⁵⁾NO₄

: C₁₂₃H₁₉₈N₃₂⁽¹⁵⁾N₄O₃₆S

Guidance literature:: N-tert-butyloxycarbonylasparagine; C₂₄H₂₉N₂O₆Pol; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 0.2h;

With trifluoroacetic acid; In N,N-dimethyl-formamide;

1-(tert-butoxycarbonyl)-L-proline; t-Boc-L-valine; N-tert-butoxycarbonyl-L-leucine; N-tert-butyloxycarbonylasparagine; BOC-L-aspartic acid 4-benzyl ester; Boc-Gln-OH; Boc-Glu(OBzl)-OH; Boc-Arg(Z)2-OH; N-(tert-butyloxycarbonyl)-S-(4-methoxybenzyl)cysteine; Boc-(S)-Lys(2-Cl-Z)-OH; Nα-tert-butoxycarbonyl-1-formyl-L-tryptophan; [15N]-N-(tert-butoxycarbonyl)-L-alanine; (15N)-N^α-t-Boc-L-valine; C₁₄H₁₉⁽¹⁵⁾NO₄; Further stages;
DOI:10.1021/jacs.7b03277