8-BENZENESULFONYL-6-(PYRIDIN-2-YLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE

Base Information

Chemical Name:8-BENZENESULFONYL-6-(PYRIDIN-2-YLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE
CAS No.:612065-29-9
Molecular Formula:C19H17N3O3S
Molecular Weight:367.42
Hs Code.:
Mol file:612065-29-9.mol

Synonyms:8-BENZENESULFONYL-6-(PYRIDIN-2-YLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE

Suppliers and Price of 8-BENZENESULFONYL-6-(PYRIDIN-2-YLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
8-BENZENESULFONYL-6-(PYRIDIN-2-YLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE 95.00%
5MG
$ 498.72

Total 2 raw suppliers

Chemical Property of 8-BENZENESULFONYL-6-(PYRIDIN-2-YLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE

Chemical Property:

Vapor Pressure:1.26E-15mmHg at 25°C
Refractive Index:1.701
Boiling Point:626.8°C at 760 mmHg
Flash Point:332.9°C
PSA：89.44000
Density:1.45g/cm³
LogP:3.91970

Purity/Quality:

97% ^*data from raw suppliers

8-BENZENESULFONYL-6-(PYRIDIN-2-YLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 8-BENZENESULFONYL-6-(PYRIDIN-2-YLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE

There total 4 articles about 8-BENZENESULFONYL-6-(PYRIDIN-2-YLAMINO)-2,3-DIHYDRO-1H-INDOLIZIN-5-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 504-29-0
2-aminopyridine

: 185198-44-1
trifluoromethanesulfonic acid 8-phenylsulfonyl-5-oxo-1,2,3,5-tetrahydroindolizin-6-yl ester

: 612065-29-9
8-benzenesulfonyl-6-(pyridin-2-ylamino)-2,3-dihydro-1H-indolizin-5-one

Guidance literature:: With caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; at 100 ℃;
DOI:10.1021/ol0356338

Reference yield:

: 5535-48-8
PVS

: 612065-29-9
8-benzenesulfonyl-6-(pyridin-2-ylamino)-2,3-dihydro-1H-indolizin-5-one

Guidance literature:: Multi-step reaction with 3 steps

1: Rh(II)

2: Et₃N

3: 9,9-dimethyl-4,5-bis(diphenylphosphino)xanthene; cesium carbonate / tris(dibenzylideneacetone)palladium⁽⁰⁾ / dioxane / 100 °C

With caesium carbonate; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; rhodium⁽²⁺⁾; In 1,4-dioxane;
DOI:10.1021/jo0511492

Reference yield:

: 185198-43-0
8-(phenylsulfonyl)-6-hydroxy-2,3-dihydro-1H-indolizin-5-one

: 612065-29-9
8-benzenesulfonyl-6-(pyridin-2-ylamino)-2,3-dihydro-1H-indolizin-5-one

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N

2: 9,9-dimethyl-4,5-bis(diphenylphosphino)xanthene; cesium carbonate / tris(dibenzylideneacetone)palladium⁽⁰⁾ / dioxane / 100 °C

With caesium carbonate; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane;
DOI:10.1021/jo0511492