OCTYL 2-ACETAMIDO-2-DEOXY-B-D-GLUCOPYRANOSIDE

Base Information

• Chemical Name: OCTYL 2-ACETAMIDO-2-DEOXY-B-D-GLUCOPYRANOSIDE
• CAS No.: 147126-58-7
• Molecular Formula: C16H31 N O6
• Molecular Weight: 333.42
• Mol file: 147126-58-7.mol

Synonyms:OCTYL 2-ACETAMIDO-2-DEOXY-B-D-GLUCOPYRANOSIDE;OCTYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE;OCTYL-2-ACETAMIDO-2-DEOXY-SS-D-GLUCOPYRANOSIDE

Chemical Property of OCTYL 2-ACETAMIDO-2-DEOXY-B-D-GLUCOPYRANOSIDE

Chemical Property:

• Melting Point: 183-185?C
• PSA: 108.25000
• LogP: 0.69810
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

Octyl 2-acetamido-2-deoxy-b-D-glucopyranoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A nonionic detergent for the solubilization of membrane bound protein.

Technology Process of OCTYL 2-ACETAMIDO-2-DEOXY-B-D-GLUCOPYRANOSIDE

There total 12 articles about OCTYL 2-ACETAMIDO-2-DEOXY-B-D-GLUCOPYRANOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

n-octyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside (173725-22-9) → octyl 2-(acetylamino)-2-deoxy-β-D-glucopyranoside (147126-58-7,383417-49-0)

Guidance literature:

With sodium methylate; In methanol;

DOI:10.1023/A:1023944818406

Reference yield: 69.0%

octanol (111-87-5) + 2-methyl-(1,2-dideoxy-5,6-O-isopropylidene-α-D-glucofurano)-<2,1-d>-2-oxazoline (117177-19-2) → octyl 2-(acetylamino)-2-deoxy-β-D-glucopyranoside (147126-58-7,383417-49-0)

Guidance literature:

With 4 A molecular sieve; at 20 ℃;

DOI:10.1021/ol051523k

Reference yield:

octanol (111-87-5) + 2-acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D-glucopyranose (3006-60-8,4539-83-7,6730-10-5,7772-79-4,7784-54-5,10385-50-9,14086-90-9,26151-16-6,76375-60-5,76375-61-6,95341-98-3,95341-99-4,134451-91-5,134451-96-0,136982-81-5,145375-11-7,148347-15-3) → octyl 2-(acetylamino)-2-deoxy-β-D-glucopyranoside (147126-58-7,383417-49-0)

Guidance literature:

2-acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-β-D-glucopyranose; With trimethylsilyl trifluoromethanesulfonate; sodium hydrogencarbonate; In chloroform; water; at 20 ℃; for 5h;

octanol; With camphor-10-sulfonic acid; sodium hydrogencarbonate; In chloroform; water; 1,2-dichloro-ethane; at 60 ℃; for 2h;

sodium methylate; In 1,4-dioxane; methanol; at 20 ℃; for 1h;

upstream raw materials:

octanol

N-Acetyl-D-glucosamine

n-octyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside

2-methyl-(1,2-dideoxy-5,6-O-isopropylidene-α-D-glucofurano)-<2,1-d>-2-oxazoline

Downstream raw materials:

1-octyl 2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranoside

(R)-4-{(S)-2-[(R)-2-((2R,3R,4R,5S,6R)-3-Acetylamino-5-hydroxy-6-hydroxymethyl-2-octyloxy-tetrahydro-pyran-4-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyric acid benzyl ester

(R)-4-{(S)-2-[(R)-2-((4aR,6R,7R,8R,8aS)-7-Acetylamino-2,2-dimethyl-6-octyloxy-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yloxy)-propionylamino]-propionylamino}-4-carbamoyl-butyric acid benzyl ester

octyl 2-acetamido-3,6-di-O-benzyl-2-deoxy-β-D-glucopyranoside