(4-Decyl-2,3-difluorophenyl)boronic acid

Base Information

Chemical Name:(4-Decyl-2,3-difluorophenyl)boronic acid
CAS No.:147223-09-4
Molecular Formula:C16H25 B F2 O2
Molecular Weight:298.18
Hs Code.:
DSSTox Substance ID:DTXSID90598340
Wikidata:Q82494089
Mol file:147223-09-4.mol

Synonyms:(4-Decyl-2,3-difluorophenyl)boronic acid;147223-09-4;4-DECYL-2,3-DIFLUOROBENZENEBORONIC ACID;starbld0019312;SCHEMBL7876152;DTXSID90598340;VJSKAJBAWZZPDC-UHFFFAOYSA-N;4-decyl-2,3-difluorophenylboronic acid;(4-Decyl-2,3-Difluorophenyl)Boronicacid;4-n-Decyl-2,3-difluorophenyl boronic acid

Suppliers and Price of (4-Decyl-2,3-difluorophenyl)boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (4-Decyl-2,3-difluorophenyl)boronic acid

Chemical Property:

PSA：40.46000
LogP:3.32780
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:298.1915665
Heavy Atom Count:21
Complexity:267

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=C(C(=C(C=C1)CCCCCCCCCC)F)F)(O)O

Technology Process of (4-Decyl-2,3-difluorophenyl)boronic acid

There total 6 articles about (4-Decyl-2,3-difluorophenyl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 112-31-2
caprinaldehyde

: 147223-09-4
4-n-Decyl-2,3-difluorophenyl boronic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: n-butyllithium / hexane; tetrahydrofuran / 3 h / -78 °C

1.2: hexane; tetrahydrofuran / -78 - 20 °C

2.1: P₂O₅ / light petroleum / 20 °C

3.1: H₂ / 5 percent Pd/C / light petroleum / 12 h / 20 °C

4.1: n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C

4.2: hexane; tetrahydrofuran / -78 - 20 °C

5.1: 10 percent aq. HCl / 1 h / 20 °C

With hydrogenchloride; n-butyllithium; hydrogen; phosphorus pentoxide; palladium on activated charcoal; In tetrahydrofuran; hexane; Petroleum ether; 1.1: Metallation / 1.2: Addition / 2.1: Dehydration / 3.1: Hydrogenation / 4.1: Metallation / 4.2: Substitution / 5.1: Hydrolysis;
DOI:10.1039/a902351h

Reference yield:

: 367-11-3
ortho-difluorobenzene

: 147223-09-4
4-n-Decyl-2,3-difluorophenyl boronic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: n-butyllithium / hexane; tetrahydrofuran / 3 h / -78 °C

1.2: hexane; tetrahydrofuran / -78 - 20 °C

2.1: P₂O₅ / light petroleum / 20 °C

3.1: H₂ / 5 percent Pd/C / light petroleum / 12 h / 20 °C

4.1: n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C

4.2: hexane; tetrahydrofuran / -78 - 20 °C

5.1: 10 percent aq. HCl / 1 h / 20 °C

With hydrogenchloride; n-butyllithium; hydrogen; phosphorus pentoxide; palladium on activated charcoal; In tetrahydrofuran; hexane; Petroleum ether; 1.1: Metallation / 1.2: Addition / 2.1: Dehydration / 3.1: Hydrogenation / 4.1: Metallation / 4.2: Substitution / 5.1: Hydrolysis;
DOI:10.1039/a902351h

Reference yield:

: 147223-08-3
1-((E)-Dec-1-enyl)-2,3-difluoro-benzene

: 147223-09-4
4-n-Decyl-2,3-difluorophenyl boronic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: H₂ / 5 percent Pd/C / light petroleum / 12 h / 20 °C

2.1: n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C

2.2: hexane; tetrahydrofuran / -78 - 20 °C

3.1: 10 percent aq. HCl / 1 h / 20 °C

With hydrogenchloride; n-butyllithium; hydrogen; palladium on activated charcoal; In tetrahydrofuran; hexane; Petroleum ether; 1.1: Hydrogenation / 2.1: Metallation / 2.2: Substitution / 3.1: Hydrolysis;
DOI:10.1039/a902351h