5-Bromo-4-(4-methylphenyl)pyrimidine

Base Information

• Chemical Name: 5-Bromo-4-(4-methylphenyl)pyrimidine
• CAS No.: 149323-50-2
• Molecular Formula: C11H9 Br N2
• Molecular Weight: 249.11
• Hs Code.: 2933599090
• Mol file: 149323-50-2.mol

Synonyms:5-Bromo-4-(4-methylphenyl)pyrimidine;5-Bromo-4-p-tolylpyrimidine

Chemical Property of 5-Bromo-4-(4-methylphenyl)pyrimidine

Chemical Property:

• Vapor Pressure: 0.000143mmHg at 25°C
• Refractive Index: 1.601
• Boiling Point: 343.1°Cat760mmHg
• PKA: 0.47±0.16(Predicted)
• Flash Point: 161.3°C
• PSA: 25.78000
• Density: 1.434g/cm³
• LogP: 3.21450
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

5-Bromo-4-p-tolylpyrimidine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Bromo-4-(4-methylphenyl)pyrimidine

There total 1 articles about 5-Bromo-4-(4-methylphenyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

5-bromopyrimidine (4595-59-9) + para-bromotoluene (106-38-7) + ammonium chloride → 5-bromo-4-(p-tolyl)pyrimidine (149323-50-2)

Guidance literature:

With potassium permanganate; magnesium; In acetone;

Reference yield: 64.0%

5-bromo-4-(p-tolyl)pyrimidine (149323-50-2) + copper(l) cyanide → 5-cyano-4-(p-tolyl)pyrimidine (149323-51-3)

Guidance literature:

With hydrogenchloride; iron(III) chloride; In water; ethyl acetate; N,N-dimethyl-formamide;

upstream raw materials:

5-bromopyrimidine

para-bromotoluene

Downstream raw materials:

5-cyano-4-(p-tolyl)pyrimidine

Refernces