N-(1-Hydroxyoctadec-9-en-1-ylidene)tyrosine

Base Information

Chemical Name:N-(1-Hydroxyoctadec-9-en-1-ylidene)tyrosine
CAS No.:147732-57-8
Molecular Formula:C27H43 N O4
Molecular Weight:445.643
Hs Code.:
DSSTox Substance ID:DTXSID20933200
Mol file:147732-57-8.mol

Synonyms:ICCB5_000346;DTXSID20933200;N-(1-Hydroxyoctadec-9-en-1-ylidene)tyrosine

Suppliers and Price of N-(1-Hydroxyoctadec-9-en-1-ylidene)tyrosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-(1-Hydroxyoctadec-9-en-1-ylidene)tyrosine

Chemical Property:

Boiling Point:650.6±55.0 °C(Predicted)
PKA:3.14±0.10(Predicted)
PSA：86.63000
Density:1.039±0.06 g/cm3(Predicted)
LogP:6.93250
XLogP3:8.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:19
Exact Mass:445.31920885
Heavy Atom Count:32
Complexity:512

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCCC=CCCCCCCCC(=O)NC(CC1=CC=C(C=C1)O)C(=O)O
Isomeric SMILES:CCCCCCCCC=CCCCCCCCC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

Technology Process of N-(1-Hydroxyoctadec-9-en-1-ylidene)tyrosine

There total 5 articles about N-(1-Hydroxyoctadec-9-en-1-ylidene)tyrosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 727425-00-5
N-oleoyl-L-tyrosine methyl ester

: 147732-57-8
N-oleoyl-L-tyrosine

Guidance literature:: N-oleoyl-L-tyrosine methyl ester; With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 16h;

With hydrogenchloride; In water;
DOI:10.1007/s12039-017-1298-y

Reference yield: 70.0%

: 112-77-6
(Z)-9-octadecenoyl chloride

: 60-18-4,18875-48-4,25619-78-7,30704-25-7
L-tyrosine

: 147732-57-8
N-oleoyl-L-tyrosine

Guidance literature:: With potassium carbonate; In water; acetone; at 0 - 20 ℃;
DOI:10.1021/acs.jmedchem.8b00029

Reference yield:

: 1080-06-4
L-Tyr-OMe

: 147732-57-8
N-oleoyl-L-tyrosine

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 0.33 h / Cooling with ice

1.2: 12 h / 20 °C

2.1: lithium hydroxide / tetrahydrofuran; water / 16 h / 20 °C

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; lithium hydroxide; In tetrahydrofuran; dichloromethane; water;
DOI:10.1007/s12039-017-1298-y