5-METHYL-3-PIPERIDIN-4-YL-1H-INDOLE HCL

Base Information

• Chemical Name: 5-METHYL-3-PIPERIDIN-4-YL-1H-INDOLE HCL
• CAS No.: 149669-44-3
• Molecular Formula: C₁₄H₁₈N₂
• Molecular Weight: 214.31
• Hs Code.: 2933990090
• Mol file: 149669-44-3.mol

Synonyms:4-(5-Methyl-3-indolyl)piperidine

Chemical Property of 5-METHYL-3-PIPERIDIN-4-YL-1H-INDOLE HCL

Chemical Property:

• Boiling Point: 399.4±42.0 °C(Predicted)
• PKA: 17.24±0.30(Predicted)
• PSA: 27.82000
• Density: 1.096±0.06 g/cm3(Predicted)
• LogP: 3.27210

Purity/Quality:

97% ^*data from raw suppliers

5-Methyl-3-(Piperidin-4-Yl)-1h-IndoleHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-METHYL-3-PIPERIDIN-4-YL-1H-INDOLE HCL

There total 1 articles about 5-METHYL-3-PIPERIDIN-4-YL-1H-INDOLE HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

C19H26N2O2 → 4-(5-methyl-1H-indol-3-yl)piperidine (149669-44-3)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃;

DOI:10.1016/j.bmcl.2007.08.038

Reference yield:

5-methanesulfonyl-1-oxiranylmethyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine (400798-00-7) + 4-(5-methyl-1H-indol-3-yl)piperidine (149669-44-3) → C31H36O3F3N5S

Guidance literature:

In ethanol; at 60 - 70 ℃;

DOI:10.1016/j.bmcl.2007.08.038

Reference yield:

4-(5-methyl-1H-indol-3-yl)piperidine (149669-44-3) + toluene-3-sulfonic acid 2-(methyl-(toluene-3-sulfonyl)amino)ethyl ester (295790-40-8) → C24H31N3O2S

Guidance literature: