Tert-butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate

Base Information Edit

Chemical Name:Tert-butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate
CAS No.:149771-44-8
Molecular Formula:C11H20 N2 O2
Molecular Weight:212.292
Hs Code.:2933990090
European Community (EC) Number:815-968-7
DSSTox Substance ID:DTXSID60577768
Nikkaji Number:J1.659.869K
Mol file:149771-44-8.mol

Synonyms:149771-44-8;tert-butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate;8-Boc-3,8-diaza-bicyclo[3.2.1]octane;8-Boc-3,8-diazabicyclo[3.2.1]octane;C11H20N2O2;3,8-Diazabicyclo[3.2.1]octane-8-carboxylic acid, 1,1-dimethylethyl ester;MFCD17016708;1,1-dimethylethyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate;CYCLOHEXYLANTHRANILATE;8-t-butoxycarbonyl-3,8-diazabicyclo[3.2.1]octane;SCHEMBL178638;DTXSID60577768;HNINFCBLGHCFOJ-UHFFFAOYSA-N;MFCD04115137;AKOS005166981;AB19687;CS-W019596;GS-0910;SB20132;AM803244;SY020355;EN300-90564;A808957;J-519373;8-tert-butoxycarbonyl-3,8-diazabicyclo[3.2.1]octane;8-(tert-butoxycarbonyl)-3,8-diazabicyclo[3.2.1]octane;F2147-1665;Z1083213962;tert-Butyl 3,8-diazabicyclo-[3.2.1]octane-8-carboxylate;3,8-diaza-bicyclo[3,2,1]octane-8-carboxyli acid tert-butyl ester;3,8-diaza-bicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester

Suppliers and Price of Tert-butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
8-Boc-3,8-diaza-bicyclo[3.2.1]octane
25mg
$ 355.00

TRC
tert-Butyl3,8-Diazabicyclo[3.2.1]octane-8-carboxylate
250mg
$ 50.00

Synthonix
8-Boc-3,8-diaza-bicyclo[3.2.1]octane 95+%
5g
$ 170.00

Synthonix
8-Boc-3,8-diaza-bicyclo[3.2.1]octane 95+%
1g
$ 40.00

SynQuest Laboratories
3,8-Diazabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester
250 mg
$ 160.00

SynQuest Laboratories
3,8-Diazabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester
5 g
$ 880.00

SynQuest Laboratories
3,8-Diazabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester
1 g
$ 320.00

Matrix Scientific
tert-Butyl 3,8-diazabicyclo-[3.2.1]octane-8-carboxylate 95+%
1g
$ 245.00

Matrix Scientific
tert-Butyl 3,8-diazabicyclo-[3.2.1]octane-8-carboxylate 95+%
5g
$ 738.00

Matrix Scientific
tert-Butyl 3,8-diazabicyclo-[3.2.1]octane-8-carboxylate 95+%
250mg
$ 115.00

Total 58 raw suppliers

Chemical Property of Tert-butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate Edit

Chemical Property:

Vapor Pressure:0.002mmHg at 25°C
Refractive Index:1.494
Boiling Point:295.4oC at 760mmHg
PKA:9.53±0.20(Predicted)
Flash Point:132.5oC
PSA：41.57000
Density:1.076g/cm3
LogP:1.62440
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:212.152477885
Heavy Atom Count:15
Complexity:248

Purity/Quality:

97% ^*data from raw suppliers

8-Boc-3,8-diaza-bicyclo[3.2.1]octane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1C2CCC1CNC2
Uses tert-Butyl 3,8-Diazabicyclo[3.2.1]octane-8-carboxylate is used in preparation of isoquinolinone derivatives and pharmaceutical compounds thereof for prevention or treatment of poly(ADP-ribose)polymerase-1 (PARP-1)-associated diseases.

Technology Process of Tert-butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate

There total 16 articles about Tert-butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%