Benzamide, N-(6-amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)-4-(trifluoromethyl)-

Base Information

Chemical Name:Benzamide, N-(6-amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)-4-(trifluoromethyl)-
CAS No.:149981-35-1
Molecular Formula:C14H13 F3 N4 O3
Molecular Weight:342.27
Hs Code.:
Mol file:149981-35-1.mol

Synonyms:Benzamide, N-(6-amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)-4-(trifluoromethyl)-

Suppliers and Price of Benzamide, N-(6-amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)-4-(trifluoromethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Benzamide, N-(6-amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)-4-(trifluoromethyl)-

Chemical Property:

PKA:10.28±0.20(Predicted)
PSA：99.12000
Density:1.51±0.1 g/cm3(Predicted)
LogP:1.59150

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzamide, N-(6-amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)-4-(trifluoromethyl)-

There total 1 articles about Benzamide, N-(6-amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinyl)-4-(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 5440-00-6
4,5-Diamino-1,3-dimethyluracil

: 329-15-7
4-trifluoromethyl-phenyl acetyl chloride

: 149981-35-1
6-amino-5-<<4-(trifluoromethyl)benzoyl>amino>-1,3-dimethyluracil

Guidance literature:: With pyridine; for 4h; Ambient temperature;
DOI:10.1021/jm00070a007

Reference yield: 71.0%

: 149981-35-1
6-amino-5-<<4-(trifluoromethyl)benzoyl>amino>-1,3-dimethyluracil

: 149981-16-8
8-<4-(trifluoromethyl)phenyl>-1,3-dimethylxanthine

Guidance literature:: With sodium hydroxide; In ethanol; for 1h; Heating;
DOI:10.1021/jm00070a007

Reference yield:

: 149981-35-1
6-amino-5-<<4-(trifluoromethyl)benzoyl>amino>-1,3-dimethyluracil

: 8-<4-(trifluoromethyl)phenyl>-1,3,7-trimethylxanthine

Guidance literature:: Multi-step reaction with 2 steps

1: 71 percent / 1 N aq. NaOH / ethanol / 1 h / Heating

2: 92 percent / K₂CO₃ / dimethylformamide / 3 h / Ambient temperature

With sodium hydroxide; potassium carbonate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00070a007