2-Propenoicacid,3-[[(1,1-dimethylethoxy)carbonyl]amino]-,(E)-(9CI)

Base Information

• Chemical Name: 2-Propenoicacid,3-[[(1,1-dimethylethoxy)carbonyl]amino]-,(E)-(9CI)
• CAS No.: 151292-70-5
• Molecular Formula: C₈H₁₃NO₄
• Molecular Weight: 187.196
• Mol file: 151292-70-5.mol

Synonyms:2-Propenoicacid,3-[[(1,1-dimethylethoxy)carbonyl]amino]-,(E)-(9CI)

Chemical Property of 2-Propenoicacid,3-[[(1,1-dimethylethoxy)carbonyl]amino]-,(E)-(9CI)

Chemical Property:

• Boiling Point: 288.0±32.0 °C(Predicted)
• PKA: 6.95±0.70(Predicted)
• Density: 1.161±0.06 g/cm3(Predicted)

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propenoicacid,3-[[(1,1-dimethylethoxy)carbonyl]amino]-,(E)-(9CI)

There total 8 articles about 2-Propenoicacid,3-[[(1,1-dimethylethoxy)carbonyl]amino]-,(E)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

Dehydro N-tert-butyloxycarbonyl β-alaninate de methyle (151292-67-0) → cis N-tert-butyloxycarbonyl dehydro β-alanine (151292-68-1,151292-70-5) + trans N-tert-butyloxycarbonyl dehydro β-alanine (151292-70-5)

Guidance literature:

With sodium hydroxide; In methanol; for 3h; Ambient temperature;

Reference yield: 14.0%

Dehydro N-tert-butyloxycarbonyl β-alaninate de methyle (151292-67-0) → cis N-tert-butyloxycarbonyl dehydro β-alanine (151292-68-1,151292-70-5) + trans N-tert-butyloxycarbonyl dehydro β-alanine (151292-70-5)

Guidance literature:

With sodium hydroxide; In methanol; for 3h; Ambient temperature;

Reference yield:

3-endo-N-tert-butyloxycarbonylaminobicyclo<2.2.1>hept-5-ene-2-endo carboxylate de methyle → cis N-tert-butyloxycarbonyl dehydro β-alanine (151292-68-1,151292-70-5)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene / 0.5 h / 160 °C

2: 81 percent / aq. 2N NaOH / methanol / 3 h / Ambient temperature

With sodium hydroxide; In methanol; benzene;

upstream raw materials:

Dehydro N-tert-butyloxycarbonyl β-alaninate de methyle

Downstream raw materials:

3-oxauracil