5-Thiazolecarboxylic acid, 4-bromo-, ethyl ester

Base Information

• Chemical Name: 5-Thiazolecarboxylic acid, 4-bromo-, ethyl ester
• CAS No.: 152300-60-2
• Molecular Formula: C₆H₆BrNO₂S
• Molecular Weight: 236.089
• Hs Code.: 2934100090
• Mol file: 152300-60-2.mol

Synonyms:5-Thiazolecarboxylic acid, 4-bromo-, ethyl ester;5-Thiazolecarboxylicacid,4-bromo-,ethylester(9CI);4-Bromo-5-thiazolecarboxylic acid ethyl ester;Ethyl 4-bromo-5-thiazolecarboxylate;ethyl 4-broMo-1,3-thiazole-5-carboxylate;4-BroMo-thiazole-5-carboxylic acid ethyl ester;ethyl 4-bromothiazole-5-carboxylate

Chemical Property of 5-Thiazolecarboxylic acid, 4-bromo-, ethyl ester

Chemical Property:

• Vapor Pressure: 0.00224mmHg at 25°C
• Refractive Index: 1.569
• Boiling Point: 289.1 °C at 760 mmHg
• PKA: -1.87±0.10(Predicted)
• Flash Point: 128.7 °C
• PSA: 67.43000
• Density: 1.654 g/cm³
• LogP: 2.08230

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Bromo-5-thiazolecarboxylicacidethylester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Thiazolecarboxylic acid, 4-bromo-, ethyl ester

There total 1 articles about 5-Thiazolecarboxylic acid, 4-bromo-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C6H7N3O2S*H(1+) → ethyl 4?bromo?5?thiazolecarboxylate (152300-60-2)

Guidance literature:

With hydrogen bromide; In acetonitrile;

Reference yield: 74.95%

ethyl 4?bromo?5?thiazolecarboxylate (152300-60-2) + 2-tri-n-butylstannylpyridine (17997-47-6) → C11H10N2O2S

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 105 ℃; for 14h;

Reference yield: 12.61%

4-phenyl-1H-pyrazole (10199-68-5) + ethyl 4?bromo?5?thiazolecarboxylate (152300-60-2) → C15H13N3O2S + C13H9N3O2S

Guidance literature:

With caesium carbonate; In toluene; at 110.6 ℃; for 16h;

Refernces