1-(2-Naphthalen-2-ylquinolin-4-yl)ethanone

Base Information

Chemical Name:1-(2-Naphthalen-2-ylquinolin-4-yl)ethanone
CAS No.:6317-99-3
Molecular Formula:C₂₁H₁₅NO
Molecular Weight:297.356
Hs Code.:
NSC Number:25685
DSSTox Substance ID:DTXSID00282384
Wikidata:Q82016641

Synonyms:6317-99-3;1-(2-(Naphthalen-2-yl)quinolin-4-yl)ethanone;1-(2-naphthalen-2-ylquinolin-4-yl)ethanone;NSC25685;SCHEMBL13199980;DTXSID00282384;NSC-25685

Suppliers and Price of 1-(2-Naphthalen-2-ylquinolin-4-yl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1-(2-Naphthalen-2-ylquinolin-4-yl)ethanone

Chemical Property:

Vapor Pressure:1.51E-10mmHg at 25°C
Boiling Point:510.7°C at 760 mmHg
Flash Point:263.2°C
Density:1.2g/cm³
XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:297.115364102
Heavy Atom Count:23
Complexity:434

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=NC2=CC=CC=C21)C3=CC4=CC=CC=C4C=C3

Technology Process of 1-(2-Naphthalen-2-ylquinolin-4-yl)ethanone

There total 7 articles about 1-(2-Naphthalen-2-ylquinolin-4-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 97674-02-7
tributyl(1-ethoxyvinyl)stannane

: 4-chloro-2-(2-naphthyl)quinoline

: 6317-99-3
2-(2-naphthyl)-4-acetylquinoline

Guidance literature:: 4-chloro-2-(2-naphthyl)quinoline; With triphenylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In toluene; at 20 ℃; for 0.25h;

tributyl(1-ethoxyvinyl)stannane; In toluene; at 130 ℃; for 16h; Inert atmosphere;

With hydrogenchloride; In water; at 20 ℃; for 72h; Inert atmosphere;

Reference yield:

: 3-(2-[2]naphthyl-[4]quinolyl)-3-oxo-propionic acid ethyl ester

: 6317-99-3
2-(2-naphthyl)-4-acetylquinoline

Guidance literature:: With sulfuric acid; water;
DOI:10.1021/ja01213a043

Reference yield:

: 88-17-5
2-(trifluoromethyl)benzenamine

: 6317-99-3
2-(2-naphthyl)-4-acetylquinoline

Guidance literature:: Multi-step reaction with 5 steps

1.1: toluene-4-sulfonic acid / toluene / 15 h / Reflux; Inert atmosphere

2.1: tetrahydrofuran / 0.83 h / Reflux

3.1: tetrahydrofuran / 5.75 h / Reflux

4.1: trichlorophosphate; phosphorus pentachloride / 1.25 h / Reflux; Inert atmosphere

5.1: bis(dibenzylideneacetone)-palladium⁽⁰⁾; triphenylphosphine / toluene / 0.25 h / 20 °C

5.2: 16 h / 130 °C / Inert atmosphere

5.3: 72 h / 20 °C / Inert atmosphere

With phosphorus pentachloride; toluene-4-sulfonic acid; triphenylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; trichlorophosphate; In tetrahydrofuran; toluene;