6-BROMOMETHYL INDAZOLE

Base Information

• Chemical Name: 6-BROMOMETHYL INDAZOLE
• CAS No.: 152626-91-0
• Molecular Formula: C₈H₇BrN₂
• Molecular Weight: 211.061
• Hs Code.: 2933990090
• Mol file: 152626-91-0.mol

Synonyms:6-BROMOMETHYL INDAZOLE

Chemical Property of 6-BROMOMETHYL INDAZOLE

Chemical Property:

• Refractive Index: 1.721
• Boiling Point: 355.8°Cat760mmHg
• PKA: 13.57±0.40(Predicted)
• Flash Point: 169°C
• PSA: 28.68000
• Density: 1.694g/cm³
• LogP: 2.45780

Purity/Quality:

98%min ^*data from raw suppliers

6-(Bromomethyl)-1H-indazole hydrobromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-BROMOMETHYL INDAZOLE

There total 2 articles about 6-BROMOMETHYL INDAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

6-(hydroxymethyl)-1H-indazole (916902-55-1) → 6-(bromomethyl)-1H-indazole (152626-91-0)

Guidance literature:

With hydrogen bromide; acetic acid; at 120 ℃; for 1h; Inert atmosphere;

DOI:10.1515/hc-2014-0180

Reference yield: 84.0%

1-acetyl-6-(acetoxymethyl)indazole (368426-62-4) → 6-(bromomethyl)-1H-indazole (152626-91-0)

Guidance literature:

In hydrogen bromide;

upstream raw materials:

1-acetyl-6-(acetoxymethyl)indazole

6-(hydroxymethyl)-1H-indazole

Refernces

• 1、 -. "Substituted hydrazinyl heteroaromatic inhibitors of thrombin". . . Retrieved 2008/06/13.