6-Bromopyrido[2,3-d]pyrimidine-2,4-diamine

Base Information

Chemical Name:6-Bromopyrido[2,3-d]pyrimidine-2,4-diamine
CAS No.:152941-69-0
Molecular Formula:C7H6 Br N5
Molecular Weight:240.062
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80590171
Wikidata:Q82483864
Mol file:152941-69-0.mol

Synonyms:6-Bromopyrido[2,3-d]pyrimidine-2,4-diamine;152941-69-0;SCHEMBL5352607;AMY1708;DTXSID80590171;A883859

Suppliers and Price of 6-Bromopyrido[2,3-d]pyrimidine-2,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
6-Bromopyrido[2,3-d]pyrimidine-2,4-diamine 95+%
1g
$ 1081.00

American Custom Chemicals Corporation
6-BROMOPYRIDO[2,3-D]PYRIMIDINE-2,4-DIAMINE 95.00%
5G
$ 3759.53

American Custom Chemicals Corporation
6-BROMOPYRIDO[2,3-D]PYRIMIDINE-2,4-DIAMINE 95.00%
1G
$ 1697.85

Alichem
6-Bromopyrido[2,3-d]pyrimidine-2,4-diamine
1g
$ 901.25

Total 8 raw suppliers

Chemical Property of 6-Bromopyrido[2,3-d]pyrimidine-2,4-diamine

Chemical Property:

PSA：90.71000
LogP:2.11410
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:238.98066
Heavy Atom Count:13
Complexity:190

Purity/Quality:

97% ^*data from raw suppliers

6-Bromopyrido[2,3-d]pyrimidine-2,4-diamine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=NC2=NC(=NC(=C21)N)N)Br

Technology Process of 6-Bromopyrido[2,3-d]pyrimidine-2,4-diamine

There total 5 articles about 6-Bromopyrido[2,3-d]pyrimidine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 152941-68-9
4-amino-6-bromo-2-pivaloylamino-5-deazapteridine

: 152941-69-0
2,4-diamino-6-bromopyrido<2,3-d>pyrimidine

Guidance literature:: With ammonium hydroxide; In 1,4-dioxane; for 120h; Ambient temperature;

Reference yield:

: 1004-38-2
2,4,6-triaminopyrimidine

: 2065-75-0
2-Bromo-malonaldehyde

: 152941-69-0
2,4-diamino-6-bromopyrido<2,3-d>pyrimidine

Guidance literature:: With hydrogenchloride; In ethanol; for 0.0833333h; Yield given; Heating;
DOI:10.1002/jhet.5570280717

Reference yield:

: 116387-22-5
2-pivaloylamino-6-bromo-4(3H)-pyrido[2,3-d]pyrimidinone

: 152941-69-0
2,4-diamino-6-bromopyrido<2,3-d>pyrimidine

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / p-chlorophenylphosphoro-dichloridate, pyridine / 24 h / Ambient temperature

2: 92 percent / Na / 0.25 h / Ambient temperature

3: 95 percent / aq. NH₃ / dioxane / 12 h / Ambient temperature

4: 81 percent / aq. NH₃ / dioxane / 120 h / Ambient temperature

With pyridine; ammonium hydroxide; sodium; 4-chlorophenylphosphorodichloridate; In 1,4-dioxane;