2-Chloro-4-iodopyridin-3-amine

Base Information

Chemical Name:2-Chloro-4-iodopyridin-3-amine
CAS No.:153034-93-6
Molecular Formula:C5H4 Cl I N2
Molecular Weight:254.458
Hs Code.:
European Community (EC) Number:852-519-4
DSSTox Substance ID:DTXSID50433849
Nikkaji Number:J566.229J
Wikidata:Q82248100
Mol file:153034-93-6.mol

Synonyms:2-chloro-4-iodopyridin-3-amine;153034-93-6;3-Pyridinamine, 2-chloro-4-iodo-;3-Pyridinamine,2-chloro-4-iodo-;3-AMINO-2-CHLORO-4-IODOPYRIDINE;SCHEMBL12263788;2-chloro-4-iodo-3-pyridinamine;DTXSID50433849;FT-0760004;EN300-93171

Suppliers and Price of 2-Chloro-4-iodopyridin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-CHLORO-4-IODOPYRIDIN-3-AMINE 95.00%
5MG
$ 502.00

Alichem
3-Amino-2-chloro-4-iodopyridine
1g
$ 3155.55

Alichem
3-Amino-2-chloro-4-iodopyridine
250mg
$ 940.80

Total 6 raw suppliers

Chemical Property of 2-Chloro-4-iodopyridin-3-amine

Chemical Property:

Boiling Point:333.4±42.0 °C(Predicted)
PKA:2.25±0.10(Predicted)
PSA：38.91000
Density:2.139±0.06 g/cm3(Predicted)
LogP:2.50300
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:253.91077
Heavy Atom Count:9
Complexity:101

Purity/Quality:

98% ^*data from raw suppliers

2-CHLORO-4-IODOPYRIDIN-3-AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=C(C(=C1I)N)Cl

Technology Process of 2-Chloro-4-iodopyridin-3-amine

There total 1 articles about 2-Chloro-4-iodopyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 153034-92-5
3-Azido-2-chloro-4-iodopyridine

: 153034-93-6
3-Amino-2-chloro-4-iodopyridine

Guidance literature:: With piperidine; hydrogen sulfide; In methanol; at 10 - 20 ℃; for 0.5h;
DOI:10.1021/jo00079a031

Reference yield: 85.0%

: 153034-93-6
3-Amino-2-chloro-4-iodopyridine

: 168618-42-6
(2-methylsulfanylphenyl)boronic acid

: C₁₂H₁₁ClN₂S

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; at 100 ℃; for 12h;

Reference yield:

: 103681-98-7
2-diisopropylaminocarbonylphenylboronic acid

: 153034-93-6
3-Amino-2-chloro-4-iodopyridine

: 153035-13-3
N,N-Diisopropyl-2-(3-amino-2-chloro-4-pyridyl)benzamide

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; Yield given. Multistep reaction; 1.) ethanol, toluene, 0.5 h, 2.) reflux, 24 h;
DOI:10.1021/jo00079a031