Z-Asp(OtBu)-bromomethyl ketone

Base Information

Chemical Name:Z-Asp(OtBu)-bromomethyl ketone
CAS No.:153088-76-7
Molecular Formula:C17H22 Br N O5
Molecular Weight:400.269
Hs Code.:
DSSTox Substance ID:DTXSID60427294
Wikidata:Q82239979
Mol file:153088-76-7.mol

Synonyms:153088-76-7;Z-Asp(OtBu)-bromomethyl ketone;Z-Asp(OtBu)-bromomethylketone;tert-butyl (3S)-5-bromo-4-oxo-3-(phenylmethoxycarbonylamino)pentanoate;Z-L-aspartic acid beta-tert-butyl ester bromomethylketone;SCHEMBL79537;DTXSID60427294;PBVFTOAYKLEQQO-ZDUSSCGKSA-N;BDBM512561;acs.jmedchem.1c00409_ST.154;MFCD00672490;AKOS025294582;(S)-tert-butyl 3-(benzyloxycarbonylamino)-5-bromo-4-oxopentanoate;(S)-3-benzyloxycarbonylamino-5-bromo-4-oxo-pentanoic acid tert-butyl ester;t-butyl (3s)-3-[[(benzyloxy)carbonyl]amino]-5-bromo-4-oxo-pentanoate

Suppliers and Price of Z-Asp(OtBu)-bromomethyl ketone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biosynth Carbosynth
Z-Asp(OtBu)-bromomethylketone
250 mg
$ 550.00

Biosynth Carbosynth
Z-Asp(OtBu)-bromomethylketone
100 mg
$ 300.00

Biosynth Carbosynth
Z-Asp(OtBu)-bromomethylketone
50 mg
$ 200.00

Biosynth Carbosynth
Z-Asp(OtBu)-bromomethylketone
25 mg
$ 150.00

Biosynth Carbosynth
Z-Asp(OtBu)-bromomethylketone
10 mg
$ 100.00

American Custom Chemicals Corporation
Z-ASP(OTBU)-BROMOMETHYLKETONE 95.00%
1MG
$ 664.82

American Custom Chemicals Corporation
Z-ASP(OTBU)-BROMOMETHYLKETONE 95.00%
1G
$ 664.52

American Custom Chemicals Corporation
Z-ASP(OTBU)-BROMOMETHYLKETONE 95.00%
5MG
$ 1001.40

AK Scientific
Z-Asp(OtBu)-bromomethylketone
250mg
$ 792.00

Total 7 raw suppliers

Chemical Property of Z-Asp(OtBu)-bromomethyl ketone

Chemical Property:

PSA：81.70000
LogP:3.36810
Storage Temp.:−20°C
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:399.06814
Heavy Atom Count:24
Complexity:441

Purity/Quality:

98%Min ^*data from raw suppliers

Z-Asp(OtBu)-bromomethylketone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)CC(C(=O)CBr)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES:CC(C)(C)OC(=O)C[C@@H](C(=O)CBr)NC(=O)OCC1=CC=CC=C1

Technology Process of Z-Asp(OtBu)-bromomethyl ketone

There total 11 articles about Z-Asp(OtBu)-bromomethyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 118248-02-5
Z-Asp(OBut)-CHN₂

: 153088-76-7
(S)-3-benzyloxycarbonylamino-5-bromo-4-oxo-pentanoic acid tert-butyl ester

Guidance literature:: With hydrogen bromide; acetic acid; In tetrahydrofuran; diethyl ether; at 0 ℃; for 0.5h;

Reference yield: 100.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 153088-76-7
(S)-3-benzyloxycarbonylamino-5-bromo-4-oxo-pentanoic acid tert-butyl ester

Guidance literature:: Z-D(tBu)-OH; With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; at -15 ℃; for 0.333333h;

diazomethane; In tetrahydrofuran; diethyl ether; at 0 ℃; for 0.5h;

With hydrogen bromide; acetic acid; In tetrahydrofuran; diethyl ether; at 0 ℃; for 0.5 - 1h;

Reference yield: 76.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 5545-52-8
Z-D(tBu)-OH

: 153088-76-7
(S)-3-benzyloxycarbonylamino-5-bromo-4-oxo-pentanoic acid tert-butyl ester

Guidance literature:: Z-D(tBu)-OH; With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; at -10 ℃; for 0.666667h; Inert atmosphere;

diazomethane; In diethyl ether; at 0 - 20 ℃; for 2.33333h; Inert atmosphere;

With hydrogen bromide; acetic acid; In diethyl ether; at 0 - 20 ℃; for 1h;