N-[(2R,3R,4S)-3,4,6-trihydroxy-1,5-dioxohexan-2-yl]acetamide

Base Information

Chemical Name:N-[(2R,3R,4S)-3,4,6-trihydroxy-1,5-dioxohexan-2-yl]acetamide
CAS No.:153373-83-2
Molecular Formula:C₈H₁₃NO₆
Molecular Weight:219.194
Hs Code.:
Mol file:153373-83-2.mol

Synonyms:153373-83-2;N-[(2R,3R,4S)-3,4,6-trihydroxy-1,5-dioxohexan-2-yl]acetamide;SCHEMBL4623344

Suppliers and Price of N-[(2R,3R,4S)-3,4,6-trihydroxy-1,5-dioxohexan-2-yl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-[(2R,3R,4S)-3,4,6-trihydroxy-1,5-dioxohexan-2-yl]acetamide

Chemical Property:

Boiling Point:636.5±55.0 °C(Predicted)
PKA:11.75±0.20(Predicted)
PSA：123.93000
Density:1.417±0.06 g/cm3(Predicted)
LogP:-2.63590
XLogP3:-3.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:219.07428713
Heavy Atom Count:15
Complexity:254

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC(C=O)C(C(C(=O)CO)O)O
Isomeric SMILES:CC(=O)N[C@@H](C=O)[C@H]([C@@H](C(=O)CO)O)O

Technology Process of N-[(2R,3R,4S)-3,4,6-trihydroxy-1,5-dioxohexan-2-yl]acetamide

There total 5 articles about N-[(2R,3R,4S)-3,4,6-trihydroxy-1,5-dioxohexan-2-yl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1012331-07-5
methyl (5R/S)-2-acetamido-5-C-benzyloxy-2-deoxy-β-D-xylo-hexopyranoside

: 153373-83-2
N-((1R,2R,3S)-1-Formyl-2,3,5-trihydroxy-4-oxo-pentyl)-acetamide

Guidance literature:: With methanol; water; hydrogen; palladium hydroxide on carbon; under 760.051 Torr; Product distribution / selectivity;

Reference yield:

: 50605-03-3
methyl 2-acetamido-2-deoxy-5,6-O-isopropylidene-β-D-glucofuranoside

: 153373-83-2
N-((1R,2R,3S)-1-Formyl-2,3,5-trihydroxy-4-oxo-pentyl)-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / acetic acid; H₂O / 5 h / Ambient temperature

2: 1.) dibutyltin oxide, 2.) Br₂, tributyltin methoxide / 1.) 0 deg C, 2.) CH₂Cl₂

3: aq. H₂SO₄ / 3.25 h / 60 °C

With bromine; tributyltin methoxide; di(n-butyl)tin oxide; In sulfuric acid; water; acetic acid;
DOI:10.1016/S0040-4020(01)80229-5

Reference yield:

: 5517-54-4
methyl 2-acetamido-2-deoxy-β-D-glucofuranoside

: 153373-83-2
N-((1R,2R,3S)-1-Formyl-2,3,5-trihydroxy-4-oxo-pentyl)-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) dibutyltin oxide, 2.) Br₂, tributyltin methoxide / 1.) 0 deg C, 2.) CH₂Cl₂

2: aq. H₂SO₄ / 3.25 h / 60 °C

With bromine; tributyltin methoxide; di(n-butyl)tin oxide; In sulfuric acid;
DOI:10.1016/S0040-4020(01)80229-5