2-methylcyclopentanamine hydrochloride

Base Information

• Chemical Name: 2-methylcyclopentanamine hydrochloride
• CAS No.: 5454-76-2
• Molecular Formula: C₆H₁₃N*ClH
• Molecular Weight: 135.637
• Mol file: 5454-76-2.mol

Synonyms:Cyclopentanamine,2-methyl-, hydrochloride (9CI); Cyclopentylamine, 2-methyl-, hydrochloride(6CI); (2-Methylcyclopentyl)amine hydrochloride; NSC 23231

Chemical Property of 2-methylcyclopentanamine hydrochloride

Chemical Property:

• Vapor Pressure: 14.4mmHg at 25°C
• Boiling Point: 121.7°C at 760 mmHg
• Flash Point: 9.9°C
• PSA: 26.02000
• Density: 0.852g/cm³
• LogP: 2.63600

Purity/Quality:

98%min ^*data from raw suppliers

2-methylcyclopentan-1-aminehydrochloride ^*data from reagent suppliers

Safty Information:

• Statements: 41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-methylcyclopentanamine hydrochloride

There total 5 articles about 2-methylcyclopentanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

→ anti-2-methylcyclopentylamine hydrochloride (5454-76-2,102778-36-9,102778-37-0,104485-20-3,115151-94-5)

Guidance literature:

Reference yield:

t-butyl (+/-)-(1S,4R)-2-oxa-3-azabicyclo[2.2.1]hept-5-ene-3-carboxylate → anti-2-methylcyclopentylamine hydrochloride (5454-76-2,102778-36-9,102778-37-0,104485-20-3,115151-94-5)

Guidance literature:

Multi-step reaction with 4 steps

1: copper(II) chloride / tetrahydrofuran

2: TiCl₃

3: H₂ / Pd/C

4: HCl / diethyl ether

With hydrogenchloride; titanium(III) chloride; hydrogen; copper dichloride; palladium on activated charcoal; In tetrahydrofuran; diethyl ether;

DOI:10.1021/jo016275u

Reference yield:

((1R,2R)-2-Methyl-cyclopent-3-enyl)-carbamic acid tert-butyl ester → anti-2-methylcyclopentylamine hydrochloride (5454-76-2,102778-36-9,102778-37-0,104485-20-3,115151-94-5)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Pd/C

2: HCl / diethyl ether

With hydrogenchloride; hydrogen; palladium on activated charcoal; In diethyl ether;

DOI:10.1021/jo016275u

Refernces

• 1、 -. "3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands". Page 171. . Retrieved 2008/06/13.