2H-Pyran-2,4-diol, 2-ethyltetrahydro-3,5-dimethyl-6-(1-methylethyl)-, (2S,3R,4R,5S,6R)- (9CI)

Base Information

Chemical Name:2H-Pyran-2,4-diol, 2-ethyltetrahydro-3,5-dimethyl-6-(1-methylethyl)-, (2S,3R,4R,5S,6R)- (9CI)
CAS No.:604791-14-2
Molecular Formula:C12H24O3
Molecular Weight:216.31716
Hs Code.:
Mol file:604791-14-2.mol

Synonyms:2H-Pyran-2,4-diol, 2-ethyltetrahydro-3,5-dimethyl-6-(1-methylethyl)-, (2S,3R,4R,5S,6R)- (9CI)

Suppliers and Price of 2H-Pyran-2,4-diol, 2-ethyltetrahydro-3,5-dimethyl-6-(1-methylethyl)-, (2S,3R,4R,5S,6R)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2H-Pyran-2,4-diol, 2-ethyltetrahydro-3,5-dimethyl-6-(1-methylethyl)-, (2S,3R,4R,5S,6R)- (9CI)

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2H-Pyran-2,4-diol, 2-ethyltetrahydro-3,5-dimethyl-6-(1-methylethyl)-, (2S,3R,4R,5S,6R)- (9CI)

There total 6 articles about 2H-Pyran-2,4-diol, 2-ethyltetrahydro-3,5-dimethyl-6-(1-methylethyl)-, (2S,3R,4R,5S,6R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 604791-26-6
(3R,4R,5S,6S,7R)-2,4,6-Trimethyl-nonane-3,5,7-triol

: (4S,5S,6R)-5-Hydroxy-2,4,6-trimethyl-nonane-3,7-dione

: 604791-14-2
(2S,3R,4R,5S,6R)-2-Ethyl-6-isopropyl-3,5-dimethyl-tetrahydro-pyran-2,4-diol

Guidance literature:: at -78 ℃;
DOI:10.1016/S0040-4039(03)01351-0

Reference yield:

: 145937-05-9
(2S,3R)-3-(tert-butyldimethylsilyloxy)-N-methoxy-N,2-dimethylpentanamide

: 604791-14-2
(2S,3R,4R,5S,6R)-2-Ethyl-6-isopropyl-3,5-dimethyl-tetrahydro-pyran-2,4-diol

Guidance literature:: Multi-step reaction with 5 steps

1: 88 percent / EtMgBr / tetrahydrofuran / 0 °C

2: (c-hex)2BCl; Et₃N / -78 °C

3: Zn(BH₄)2 / tetrahydrofuran / -20 °C

4: 97 percent / MeOH; Dowex-50

5: 40 percent / -78 °C

With methanol; zinc(II) tetrahydroborate; Dowex-50; dicyclohexylboron chloride; ethylmagnesium bromide; triethylamine; In tetrahydrofuran; 5: Swern oxidation;
DOI:10.1016/S0040-4039(03)01351-0

Reference yield:

: 124356-91-8
(4S,2'S,3'R)-3-(2'-methyl-3'-hydroxypentanoyl)-4-benzyl-2-oxazolidinone

: 604791-14-2
(2S,3R,4R,5S,6R)-2-Ethyl-6-isopropyl-3,5-dimethyl-tetrahydro-pyran-2,4-diol

Guidance literature:: Multi-step reaction with 6 steps

1.1: Me₃Al; MeONHMe*HCl / tetrahydrofuran / 0 °C

1.2: 81 percent / imidazole / dimethylformamide / 25 °C

2.1: 88 percent / EtMgBr / tetrahydrofuran / 0 °C

3.1: (c-hex)2BCl; Et₃N / -78 °C

4.1: Zn(BH₄)2 / tetrahydrofuran / -20 °C

5.1: 97 percent / MeOH; Dowex-50

6.1: 40 percent / -78 °C

With methanol; zinc(II) tetrahydroborate; Dowex-50; dicyclohexylboron chloride; ethylmagnesium bromide; trimethylaluminum; N,O-dimethylhydroxylamine*hydrochloride; triethylamine; In tetrahydrofuran; 6.1: Swern oxidation;
DOI:10.1016/S0040-4039(03)01351-0