1-(2,5-Difluorophenyl)ethanamine

Base Information

Chemical Name:1-(2,5-Difluorophenyl)ethanamine
CAS No.:603951-44-6
Molecular Formula:C8H9F2N
Molecular Weight:157.1605664
Hs Code.:2921499090
European Community (EC) Number:815-909-5
DSSTox Substance ID:DTXSID90398584
Mol file:603951-44-6.mol

Synonyms:1-(2,5-difluorophenyl)ethanamine;603951-44-6;1-(2,5-Difluorophenyl)ethylamine;1-(2,5-difluorophenyl)ethan-1-amine;SCHEMBL506641;Benzenemethanamine, 2,5-difluoro-alpha-methyl- (9CI);DTXSID90398584;BMIRIPDNKQHPQG-UHFFFAOYSA-N;MFCD05215243;AKOS000124144;FS-4765;SB45471;CS-0154128;EN300-33187;N12219

Suppliers and Price of 1-(2,5-Difluorophenyl)ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(2,5-Difluorophenyl)ethanamine
100mg
$ 45.00

Crysdot
1-(2,5-Difluorophenyl)ethylamine 95+%
5g
$ 318.00

American Custom Chemicals Corporation
1-(2,5-DIFLUOROPHENYL)ETHANAMINE 95.00%
5G
$ 1421.65

American Custom Chemicals Corporation
1-(2,5-DIFLUOROPHENYL)ETHANAMINE 95.00%
2.5G
$ 1147.43

American Custom Chemicals Corporation
1-(2,5-DIFLUOROPHENYL)ETHANAMINE 95.00%
1G
$ 808.89

Ambeed
1-(2,5-Difluorophenyl)ethylamine 95+%
250mg
$ 40.00

Ambeed
1-(2,5-Difluorophenyl)ethylamine 95+%
100mg
$ 27.00

Ambeed
1-(2,5-Difluorophenyl)ethylamine 95+%
1g
$ 90.00

Ambeed
1-(2,5-Difluorophenyl)ethylamine 95+%
5g
$ 431.00

Alichem
1-(2,5-Difluorophenyl)ethylamine
5g
$ 343.47

Total 6 raw suppliers

Chemical Property of 1-(2,5-Difluorophenyl)ethanamine

Chemical Property:

PSA：26.02000
LogP:2.68480
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:157.07030562
Heavy Atom Count:11
Complexity:129

Purity/Quality:

99%+ ^*data from raw suppliers

1-(2,5-Difluorophenyl)ethanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=C(C=CC(=C1)F)F)N

Technology Process of 1-(2,5-Difluorophenyl)ethanamine

There total 6 articles about 1-(2,5-Difluorophenyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: (R)-N-((R)-1-(2,5-difluorophenyl)ethyl)-2-methylpropane-2-sulfinamide

: 1201363-81-6,603951-44-6
(R)-1-(2,5-difluorophenyl)ethan-1-amine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane;

Reference yield:

: (S)-N-((R)-1-(2,5-difluorophenyl)ethyl)-2-methylpropane-2-sulfinamide

: 1201363-81-6,603951-44-6
(R)-1-(2,5-difluorophenyl)ethan-1-amine

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; methanol; at 0 ℃; for 1h;

Reference yield:

: 1979-36-8
2',5'-difluoroacetophenone

: 1201363-81-6,603951-44-6
(R)-1-(2,5-difluorophenyl)ethan-1-amine

Guidance literature:: Multi-step reaction with 3 steps

1: titanium(IV) tetraethanolate / tetrahydrofuran / 20 h / 70 °C / Inert atmosphere

2: lithium triethylborohydride / tetrahydrofuran / 2 h / -78 - -70 °C / Inert atmosphere

3: hydrogenchloride / methanol; 1,4-dioxane / 1 h / 0 °C

With hydrogenchloride; titanium(IV) tetraethanolate; lithium triethylborohydride; In tetrahydrofuran; 1,4-dioxane; methanol;