Cyclobutanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, (1S,2R)- (9CI)

Base Information

Chemical Name:Cyclobutanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, (1S,2R)- (9CI)
CAS No.:601501-25-1
Molecular Formula:C6H11NO3
Molecular Weight:145.15644
Hs Code.:
Mol file:601501-25-1.mol

Synonyms:Cyclobutanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, (1S,2R)- (9CI)

Suppliers and Price of Cyclobutanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, (1S,2R)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ACHEMBLOCK
(1S,2R)-1-amino-2-(hydroxymethyl)cyclobutane-1-carboxylicacid 97%
250MG
$ 1135.00

Total 1 raw suppliers

Chemical Property of Cyclobutanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, (1S,2R)- (9CI)

Chemical Property:

PSA：0.00000
LogP:0.00000

Purity/Quality:: (1S,2R)-1-amino-2-(hydroxymethyl)cyclobutane-1-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Cyclobutanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, (1S,2R)- (9CI)

There total 17 articles about Cyclobutanecarboxylic acid, 1-amino-2-(hydroxymethyl)-, (1S,2R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 601501-21-7
(1S,4R,7S)-7-tert-butyl-1-(hydroxymethyl)-6-metoxy-7-methyl-8-oxa-5-azaspiro[3.5]non-5-en-9-one

: 601501-24-0,601501-25-1,601501-27-3
(1R,2S)-1-amino-2-(hydroxymethyl)-cyclobutanecarbocylic acid

Guidance literature:: (1S,4R,7S)-7-tert-butyl-1-(hydroxymethyl)-6-metoxy-7-methyl-8-oxa-5-azaspiro[3.5]non-5-en-9-one; With trifluoroacetic acid; In water; acetonitrile; at 60 ℃; for 48h;

With sodium hydroxide; at 60 ℃; for 24h; Further stages.; ion exchange chromatography on Dowex 50W*8;
DOI:10.1002/ejoc.200200673

Reference yield: 76.0%

: 601501-20-6
(1R,4R,7S)-7-tert-butyl-1-(hydroxymethyl)-6-metoxy-7-methyl-8-oxa-5-azaspiro[3.5]non-5-en-9-one

: 601501-24-0,601501-25-1,601501-27-3
(1R,2R)-1-amino-2-(hydroxymethyl)-cyclobutanecarbocylic acid

Guidance literature:: (1R,4R,7S)-7-tert-butyl-1-(hydroxymethyl)-6-metoxy-7-methyl-8-oxa-5-azaspiro[3.5]non-5-en-9-one; With trifluoroacetic acid; In water; acetonitrile; at 60 ℃; for 48h;

With sodium hydroxide; In methanol; at 60 ℃; for 24h; Further stages.; ion exchange chromatography on Dowex 50W*8;
DOI:10.1002/ejoc.200200673

Reference yield: 76.0%

: 601501-17-1
(1R,4S,7R)-7-tert-butyl-1-(hydroxymethyl)-6-metoxy-7-methyl-8-oxa-5-azaspiro[3.5]non-5-en-9-one

: 601501-24-0,601501-25-1,601501-27-3
(1S,2R)-1-amino-2-(hydroxymethyl)-cyclobutanecarbocylic acid

Guidance literature:: (1R,4S,7R)-7-tert-butyl-1-(hydroxymethyl)-6-metoxy-7-methyl-8-oxa-5-azaspiro[3.5]non-5-en-9-one; With trifluoroacetic acid; In water; acetonitrile; at 60 ℃; for 48h;

With sodium hydroxide; In methanol; at 60 ℃; for 24h; Further stages.; ion exchange chromatography on Dowex 50W*8;
DOI:10.1002/ejoc.200200673