4-Isoxazolecarboxylicacid,3-cyclohexyl-5-methyl-,methylester(9CI)

Base Information

• Chemical Name: 4-Isoxazolecarboxylicacid,3-cyclohexyl-5-methyl-,methylester(9CI)
• CAS No.: 55278-59-6
• Molecular Formula: C₁₂H₁₇NO₃
• Molecular Weight: 223.272
• Mol file: 55278-59-6.mol

Synonyms:4-Isoxazolecarboxylicacid,3-cyclohexyl-5-methyl-,methylester(9CI)

Chemical Property of 4-Isoxazolecarboxylicacid,3-cyclohexyl-5-methyl-,methylester(9CI)

Chemical Property:

• Boiling Point: 130 °C (1 mmHg)
• PSA: 52.33000
• LogP: 2.81730

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Isoxazolecarboxylicacid,3-cyclohexyl-5-methyl-,methylester(9CI)

There total 2 articles about 4-Isoxazolecarboxylicacid,3-cyclohexyl-5-methyl-,methylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclohexanecarbaldoxime (4715-11-1) → 3-cyclohexyl-5-methyl-isoxazole-4-carboxylic acid methyl ester (55278-59-6)

Guidance literature:

Multi-step reaction with 2 steps

1: Cl₂ / CHCl₃

2: methanol / Ambient temperature

With chlorine; In methanol; chloroform;

Reference yield:

N-hydroxycyclohex-1-carbonimidoyl chloride (55278-53-0) + Na-Salz des Acetessigsaeure-methylester → 3-cyclohexyl-5-methyl-isoxazole-4-carboxylic acid methyl ester (55278-59-6)

Guidance literature:

In methanol; Ambient temperature;

Reference yield:

3-cyclohexyl-5-methyl-isoxazole-4-carboxylic acid methyl ester (55278-59-6) → 3-Cyclohexyl-methyl-isoxazol-4-carbonsaeure (55278-64-3)

Guidance literature:

With potassium hydroxide; In ethanol; for 2h; Heating;

upstream raw materials:

N-hydroxycyclohex-1-carbonimidoyl chloride

cyclohexanecarbaldoxime

Downstream raw materials:

3-Cyclohexyl-methyl-isoxazol-4-carbonsaeure

3-cyclohexyl-5-methyl-isoxazole-4-carbonyl chloride

(3-cyclohexyl-5-methyl-isoxazol-4-yl)-acetic acid