2-AMINO-3-METHYL-HEXANOIC ACID

Base Information

• Chemical Name: 2-AMINO-3-METHYL-HEXANOIC ACID
• CAS No.: 60182-96-9
• Molecular Formula: C7H15NO2
• Molecular Weight: 145.202
• Hs Code.: 2922499990
• Mol file: 60182-96-9.mol

Synonyms:2-AMINO-3-METHYL-HEXANOIC ACID

Chemical Property of 2-AMINO-3-METHYL-HEXANOIC ACID

Chemical Property:

• Melting Point: 230-233 °C
• Boiling Point: 243.4±23.0 °C(Predicted)
• PKA: 2.57±0.28(Predicted)
• PSA: 63.32000
• Density: 1.014±0.06 g/cm3(Predicted)
• LogP: 1.53480

Purity/Quality:

99% ^*data from raw suppliers

2-amino-3-methylhexanoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMINO-3-METHYL-HEXANOIC ACID

There total 8 articles about 2-AMINO-3-METHYL-HEXANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methylvaleraldehyde (123-15-9) → 2-amino-3-methylhexanoic acid (60182-96-9)

Guidance literature:

Multi-step reaction with 2 steps

1: NH₄Cl, conc NH₃ aq / H₂O / 2 h / 0 - 20 °C

2: conc. HCl / 15 h / Heating

With hydrogenchloride; ammonium hydroxide; ammonium chloride; In water;

DOI:10.1016/0040-4020(80)80113-X

Reference yield:

2-Amino-3-methyl-hexanenitrile → 2-amino-3-methylhexanoic acid (60182-96-9)

Guidance literature:

With hydrogenchloride; for 15h; Yield given; Heating;

DOI:10.1016/0040-4020(80)80113-X

Reference yield:

2-methylvaleraldehyde (123-15-9) + potassium cyanide (151-50-8) → 2-amino-3-methylhexanoic acid (60182-96-9)

Guidance literature:

With hydrogenchloride; ammonium chloride; Yield given. Multistep reaction; 1.) water, 0 - 20 degC, 2 h, 2.) water, reflux, 15 h;

upstream raw materials:

2-methylvaleraldehyde

potassium cyanide

sodium cyanide

2-methyl-2-pentenal

Downstream raw materials:

(+/-)-threo-2-acetamino-3-methylhexanoic acid

(2S,3R)-threo-2-amino-3-methylhexanoic acid

(2S,3R)-3-methylhexane-1,2-diol

(3R,5R,6S,1'R)-(-)-tetrahydro-3,5-dimethyl-6-(1'-methylbutyl)-2H-pyran-2-one