N-(2-Chlorophenyl)-3-hydroxy-2-naphthamide

Base Information

Chemical Name:N-(2-Chlorophenyl)-3-hydroxy-2-naphthamide
CAS No.:6704-40-1
Molecular Formula:C17H12ClNO2
Molecular Weight:297.74
Hs Code.:2924299090
DSSTox Substance ID:DTXSID50344643
Nikkaji Number:J40.522A
Wikidata:Q82116650
ChEMBL ID:CHEMBL582339
Mol file:6704-40-1.mol

Synonyms:6704-40-1;2-Hydroxy-3-naphthoic Acid 2-Chloroanilide;N-(2-Chlorophenyl)-3-hydroxy-2-naphthamide;N-(2-chlorophenyl)-3-hydroxynaphthalene-2-carboxamide;GNF-Pf-4815;TCMDC-123494;2-HYDROXY-3-NAPHTHOICACID2-CHLOROANILIDE;3-Hydroxy-2-naphthoic Acid 2-Chloroanilide;N-(2-Chlorophenyl)-3-hydroxy-2-naphthalenecarboxamide;ChemDiv3_000425;Oprea1_632080;Oprea1_847568;CHEMBL582339;SCHEMBL5054132;KLNUTTQQHSRBIE-UHFFFAOYSA-;DTXSID50344643;HMS1474D07;MFCD00191652;AKOS000592806;BP-10637;CS-0206898;H0783;N-(O-Chlorophenyl)-3-hydroxy-2-naphthamide;SJ000003793;2-Hydroxy-3-naphthoic Acid 2-Chlorophenylamide;N-(2-Chlorophenyl)-3-hydroxy-2-naphthamide #;T72809;SR-01000400033;SR-01000400033-1;BRD-K33674714-001-01-3;Z56779217

Suppliers and Price of N-(2-Chlorophenyl)-3-hydroxy-2-naphthamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Hydroxy-3-NaphthoicAcid2-Chloroanilide
50mg
$ 45.00

TCI Chemical
3-Hydroxy-2-naphthoic Acid 2-Chloroanilide >98.0%(T)
5g
$ 218.00

SynQuest Laboratories
2-Hydroxy-3-naphthoic acid 2-chloroanilide
5 g
$ 208.00

American Custom Chemicals Corporation
2-HYDROXY-3-NAPHTHOIC ACID 2-CHLOROANILIDE 95.00%
5MG
$ 501.93

AK Scientific
2-Hydroxy-3-naphthoicacid2-chloroanilide
5g
$ 264.00

Total 10 raw suppliers

Chemical Property of N-(2-Chlorophenyl)-3-hydroxy-2-naphthamide

Chemical Property:

Melting Point:228 °C
Boiling Point:412.4oC at 760 mmHg
Flash Point:203.2oC
PSA：49.33000
Density:1.399g/cm3
LogP:4.52410
XLogP3:4.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:297.0556563
Heavy Atom Count:21
Complexity:376

Purity/Quality:

97% ^*data from raw suppliers

2-Hydroxy-3-NaphthoicAcid2-Chloroanilide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C=C(C(=CC2=C1)C(=O)NC3=CC=CC=C3Cl)O

Technology Process of N-(2-Chlorophenyl)-3-hydroxy-2-naphthamide

There total 4 articles about N-(2-Chlorophenyl)-3-hydroxy-2-naphthamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 95-51-2
o-chloroaniline

: 92-70-6
3-Hydroxy-2-naphthoic acid

: 6704-40-1
3-hydroxynaphthalene-2-carboxylic acid(2-chlorophenyl)amide

Guidance literature:: With phosphorus trichloride; In chlorobenzene; at 100 - 130 ℃; for 0.75h; Microwave irradiation;
DOI:10.3390/molecules18077977

Reference yield:

: 1734-00-5
3-hydroxy-2-naphthoyl chloride

: 95-51-2
o-chloroaniline

: 6704-40-1
3-hydroxynaphthalene-2-carboxylic acid(2-chlorophenyl)amide

Guidance literature:: In tetrahydrofuran; for 1h; Reflux;
DOI:10.1016/j.bmc.2012.09.056

Reference yield:

: 92-70-6
3-Hydroxy-2-naphthoic acid

: 6704-40-1
3-hydroxynaphthalene-2-carboxylic acid(2-chlorophenyl)amide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 1 h / Reflux

2: tetrahydrofuran / 1 h / Reflux

With thionyl chloride; In tetrahydrofuran;
DOI:10.1016/j.bmc.2012.09.056