5-(1H-benzimidazol-2-yl)pentanoic acid

Base Information

• Chemical Name: 5-(1H-benzimidazol-2-yl)pentanoic acid
• CAS No.: 14678-78-5
• Molecular Formula: C12H14 N2 O2
• Molecular Weight: 218.25
• Hs Code.: 2933290090
• DSSTox Substance ID: DTXSID80365341
• Mol file: 14678-78-5.mol

Synonyms:14678-78-5;5-(1H-benzimidazol-2-yl)pentanoic acid;5-(1H-Benzoimidazol-2-yl)-pentanoic acid;5-(1H-1,3-benzodiazol-2-yl)pentanoic acid;5-(1H-Benzo[d]imidazol-2-yl)pentanoic acid;5-(1H-3,1-benzimidazol-3-ium-2-yl)pentanoate;ChemDiv2_003421;4-ETHYLPHENYLZINCIODIDE;SCHEMBL7433457;DTXSID80365341;1H-Benzimidazole-2-pentanoic acid;HMS1378L11;BBL011715;MFCD00612525;STK387504;AKOS000266357;CCG-202979;2-(4-CARBOXYBUTYL)BENZIMIDAZOLE;VS-03023;BB 0219130;CS-0216377;EN300-41378;E84455;Z57395496

Chemical Property of 5-(1H-benzimidazol-2-yl)pentanoic acid

Chemical Property:

• Vapor Pressure: 5.54E-11mmHg at 25°C
• Refractive Index: 1.635
• Boiling Point: 504.1°C at 760 mmHg
• Flash Point: 258.7°C
• PSA: 65.98000
• Density: 1.268g/cm³
• LogP: 2.36030
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 218.105527694
• Heavy Atom Count: 16
• Complexity: 245

Purity/Quality:

98%min ^*data from raw suppliers

5-(1H-Benzimidazol-2-yl)pentanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)NC(=N2)CCCCC(=O)O

Technology Process of 5-(1H-benzimidazol-2-yl)pentanoic acid

There total 2 articles about 5-(1H-benzimidazol-2-yl)pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

Adipic acid (124-04-9) + 1,2-diamino-benzene (95-54-5) → 5-(1H-benzoimidazol-2-yl)-pentanoic acid (14678-78-5)

Guidance literature:

With hydrogenchloride; at 80 ℃; for 4h;

Reference yield:

→ 5-(1H-benzoimidazol-2-yl)-pentanoic acid (14678-78-5)

Guidance literature:

d. Methylester, wss.-ethanol. NaOH, S. 1618;

Reference yield: 81.0%

para-dichlorobenzene (106-46-7,84348-21-0) + 5-(1H-benzoimidazol-2-yl)-pentanoic acid (14678-78-5) → 5-[1-(4-chloro-phenyl)-1H-benzoimidazol-2-yl]-pentanoic acid

Guidance literature:

With sodium hydride; In ethanol; at 40 ℃;

upstream raw materials:

Adipic acid

1,2-diamino-benzene

Refernces