1H-Indazole-1-carboxylicacid,4-amino-,methylester(9CI)

Base Information

Chemical Name:1H-Indazole-1-carboxylicacid,4-amino-,methylester(9CI)
CAS No.:581812-76-2
Molecular Formula:C9H9N3O2
Molecular Weight:191.189
Hs Code.:
Mol file:581812-76-2.mol

Synonyms:1H-Indazole-1-carboxylicacid,4-amino-,methylester(9CI)

Suppliers and Price of 1H-Indazole-1-carboxylicacid,4-amino-,methylester(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-AMINO-1H-INDAZOLE-1-CARBOXYLIC ACID METHYL ESTER 95.00%
5MG
$ 500.05

Total 1 raw suppliers

Chemical Property of 1H-Indazole-1-carboxylicacid,4-amino-,methylester(9CI)

Chemical Property:

Boiling Point:389.2±34.0 °C(Predicted)
PKA:2?+-.0.10(Predicted)
PSA：70.14000
Density:1.40±0.1 g/cm3(Predicted)
LogP:1.81420

Purity/Quality:: 4-AMINO-1H-INDAZOLE-1-CARBOXYLIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Indazole-1-carboxylicacid,4-amino-,methylester(9CI)

There total 3 articles about 1H-Indazole-1-carboxylicacid,4-amino-,methylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 581812-75-1
4-nitroindazole-1-carboxylic acid methyl ester

: 581812-76-2
4-aminoindazole-1-carboxylic acid methyl ester

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 1.5 ℃; under 2068.65 Torr;

Reference yield:

: 2942-40-7
nitro-4 indazole

: 581812-76-2
4-aminoindazole-1-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaH / dimethylformamide / 0 °C

1.2: 51 percent / dimethylformamide / 0 - 20 °C

2.1: H₂ / Pd/C / methanol / 1 h / 60 °C / 3102.97 Torr

With hydrogen; sodium hydride; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2007.04.105

Reference yield:

: 603-83-8
3-nitro-o-tolylamine

: 581812-76-2
4-aminoindazole-1-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: sodium nitrite / water; acetic acid

2: NaH / water; N,N-dimethyl-formamide

3: palladium-carbon / ethanol

With NaH; sodium nitrite; palladium-carbon; In ethanol; water; acetic acid; N,N-dimethyl-formamide;