2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol

Base Information

Chemical Name:2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol
CAS No.:566169-93-5
Molecular Formula:C14H12N2OS
Molecular Weight:256.328
Hs Code.:2934200090
UNII:K6396E6G8G
Nikkaji Number:J1.917.700I
Wikidata:Q27282003
Pharos Ligand ID:13GTHNQDL6U8
ChEMBL ID:CHEMBL93124
Mol file:566169-93-5.mol

Synonyms:((11)C)PIB;(11C)6-OH-BTA-1;11C-PIB;2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole;6-OH-BTA-1;N-methyl-(11C)2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole;N-methyl-2-(4'-methylaminophenyl)-6-hydroxybenzothiazole;PIB benzothiazole;Pittsburgh compound B

Suppliers and Price of 2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol 95+%
250mg
$ 371.00

Crysdot
2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol 95+%
100mg
$ 232.00

Chemenu
2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol 95%
100mg
$ 234.00

Chemenu
2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol 95%
1g
$ 936.00

Chemenu
2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol 95%
250mg
$ 375.00

Alichem
2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol
1g
$ 973.44

Alichem
2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol
250mg
$ 371.25

Alichem
2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol
100mg
$ 245.70

Total 12 raw suppliers

Chemical Property of 2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol

Chemical Property:

Boiling Point:475.7±51.0 °C(Predicted)
PKA:8.74±0.40(Predicted)
PSA：73.39000
Density:1.353±0.06 g/cm3(Predicted)
LogP:3.78360
Storage Temp.:2-8°C(protect from light)
XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:256.06703418
Heavy Atom Count:18
Complexity:281

Purity/Quality:

99%, ^*data from raw suppliers

2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1=CC=C(C=C1)C2=NC3=C(S2)C=C(C=C3)O
Recent ClinicalTrials:The Sleep Amyloid, Slow WAve Race and Ethnicity Study

Technology Process of 2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol

There total 13 articles about 2-(4-(Methylamino)phenyl)benzo[d]thiazol-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 401813-34-1
4-(6-methoxybenzo[d]thiazol-2-yl)-N-methylaniline

: 566169-93-5
2-(4-(methylamino)phenyl)benzo[d]thiazol-6-ol

Guidance literature:: With boron tribromide; In dichloromethane; water; at 20 ℃; for 12h;

Reference yield: 60.0%

: 1071832-31-9
C₁₆H₁₆N₂OS

: 566169-93-5
2-(4-(methylamino)phenyl)benzo[d]thiazol-6-ol

Guidance literature:: With boron tribromide; In dichloromethane; for 16h;
DOI:10.1016/j.jfluchem.2007.11.005

Reference yield:

: 1747-60-0
6-methoxybenzothiazol-2-ylamine

: 566169-93-5
2-(4-(methylamino)phenyl)benzo[d]thiazol-6-ol

Guidance literature:: Multi-step reaction with 3 steps

1: 15.3 g / aq. KOH / ethane-1,2-diol / 48 h / Heating

2: 21 percent / polyphosphoric acid / 1.5 h / 170 °C

3: 75 percent / BBr₃ / CH₂Cl₂ / 16 h / 20 °C

With potassium hydroxide; PPA; boron tribromide; In dichloromethane; ethylene glycol;
DOI:10.1021/jm030026b