2(1H)-Pyrazinone, 5,6-dihydro-1,3,5-trimethyl-, 4-oxide (9CI)

Base Information

• Chemical Name: 2(1H)-Pyrazinone, 5,6-dihydro-1,3,5-trimethyl-, 4-oxide (9CI)
• CAS No.: 566155-32-6
• Molecular Formula: C₇H₁₂N₂O₂
• Molecular Weight: 156.184
• Mol file: 566155-32-6.mol

Synonyms:2(1H)-Pyrazinone, 5,6-dihydro-1,3,5-trimethyl-, 4-oxide (9CI)

Chemical Property of 2(1H)-Pyrazinone, 5,6-dihydro-1,3,5-trimethyl-, 4-oxide (9CI)

Chemical Property:

• Melting Point: 91 - 93 °C (various solvent(s))
• PSA: 49.06000
• LogP: -0.28520

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2(1H)-Pyrazinone, 5,6-dihydro-1,3,5-trimethyl-, 4-oxide (9CI)

There total 2 articles about 2(1H)-Pyrazinone, 5,6-dihydro-1,3,5-trimethyl-, 4-oxide (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

(E)-N-allyl-2-(hydroxyimino)-N-methylpropanamide (566155-27-9,566155-29-1) → 2,4,6-trimethyl-5-oxo-2,3,4,5-tetrahydropyrazin-1-ium-1-olate (566155-32-6)

Guidance literature:

With hydroquinone; In xylene; for 20h; Heating;

DOI:10.1039/b210943n

Reference yield:

N-allyl-N-methyl-2-oxopropanamide (566155-23-5) → 2,4,6-trimethyl-5-oxo-2,3,4,5-tetrahydropyrazin-1-ium-1-olate (566155-32-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 20 percent / pyridine; NH₂OH*HCl / ethanol / 15 h / 20 °C

2: 88 percent / hydroquinone / xylene / 20 h / Heating

With pyridine; hydroxylamine hydrochloride; hydroquinone; In ethanol; xylene;

DOI:10.1039/b210943n

Reference yield: 49.0%

PVS (5535-48-8) + 2,4,6-trimethyl-5-oxo-2,3,4,5-tetrahydropyrazin-1-ium-1-olate (566155-32-6) → 3a,5,7-trimethyl-2-(phenylsulfonyl)tetrahydro-2H-isoxazolo[2,3-a]pyrazin-4(5H)-one

Guidance literature:

In toluene; for 72h; Heating;

DOI:10.1039/b210943n

upstream raw materials:

(E)-N-allyl-2-(hydroxyimino)-N-methylpropanamide

N-allyl-N-methyl-2-oxopropanamide