Furo[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-4,7-dihydro-2-[[[(2R)-2-hydroxy-2-pyrazinylethyl]methylamino]methyl]-7-methyl-4-oxo- (9CI)

Base Information

• Chemical Name: Furo[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-4,7-dihydro-2-[[[(2R)-2-hydroxy-2-pyrazinylethyl]methylamino]methyl]-7-methyl-4-oxo- (9CI)
• CAS No.: 562101-59-1
• Molecular Formula: C₂₄H₂₄ClN₅O₄
• Molecular Weight: 481.939
• Mol file: 562101-59-1.mol

Synonyms:Furo[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-4,7-dihydro-2-[[[(2R)-2-hydroxy-2-pyrazinylethyl]methylamino]methyl]-7-methyl-4-oxo- (9CI)

Chemical Property of Furo[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-4,7-dihydro-2-[[[(2R)-2-hydroxy-2-pyrazinylethyl]methylamino]methyl]-7-methyl-4-oxo- (9CI)

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Technology Process of Furo[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-4,7-dihydro-2-[[[(2R)-2-hydroxy-2-pyrazinylethyl]methylamino]methyl]-7-methyl-4-oxo- (9CI)

There total 1 articles about Furo[2,3-b]pyridine-5-carboxamide, N-[(4-chlorophenyl)methyl]-4,7-dihydro-2-[[[(2R)-2-hydroxy-2-pyrazinylethyl]methylamino]methyl]-7-methyl-4-oxo- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-2-(1-hydroxy-2-N-methylamino-ethyl)-pyrazine (556025-61-7) + C17H14Cl2N2O3 (562100-72-5) → C24H24ClN5O4 (562101-59-1)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 90 ℃;

DOI:10.1016/j.bmcl.2008.06.060

upstream raw materials:

(R)-2-(1-hydroxy-2-N-methylamino-ethyl)-pyrazine

C₁₇H₁₄Cl₂N₂O₃

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