CIS-2,6-PIPERIDINE DICARBOXYLIC ACID

Base Information

• Chemical Name: CIS-2,6-PIPERIDINE DICARBOXYLIC ACID
• CAS No.: 59234-40-1
• Molecular Formula: C₇H₁₁NO₄
• Molecular Weight: 173.169
• Mol file: 59234-40-1.mol

Synonyms:CIS-2,6-PIPERIDINE DICARBOXYLIC ACID

Chemical Property of CIS-2,6-PIPERIDINE DICARBOXYLIC ACID

Chemical Property:

• PSA: 86.63000
• LogP: -0.00490
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CIS-2,6-PIPERIDINE DICARBOXYLIC ACID

There total 11 articles about CIS-2,6-PIPERIDINE DICARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

potassium salt of (+/-)-2,3,4,5-tetrahydrodipicolinate → cis-meso-piperidine-2,6-dicarboxylic acid (59234-40-1,429661-20-1)

Guidance literature:

With hydrogen; platinum(IV) oxide; In water; for 12h; Ambient temperature;

DOI:10.1016/0040-4020(95)00618-I

Reference yield: 96.0%

Pyridine-2,6-dicarboxylic acid (499-83-2) → cis-meso-piperidine-2,6-dicarboxylic acid (59234-40-1,429661-20-1)

Guidance literature:

With hydrogen; platinum(IV) oxide; In acetic acid; for 30h; Ambient temperature;

DOI:10.1016/0040-4020(95)00618-I

Reference yield: 79.0%

meso-piperidine-2,6-dicarboxamide (99669-83-7) → cis-meso-piperidine-2,6-dicarboxylic acid (59234-40-1,429661-20-1)

Guidance literature:

With barium dihydroxide; In water; for 2h; Heating;

DOI:10.1016/0040-4020(95)00618-I

upstream raw materials:

Pyridine-2,6-dicarboxylic acid

2,6-diaminopimelic acid

meso-piperidine-2,6-dicarboxamide

(2R,6R)-2,6-diaminoheptanedioic acid

Downstream raw materials:

(+/-)-trans-piperidine-2,6-dicarboxylic acid

meso-1-((benzyloxy)carbonyl)piperidine-2,6-dicarboxylic acid

2,4-Dioxo-3-oxa-9-aza-bicyclo[3.3.1]nonane-9-carboxylic acid benzyl ester

2,4-dioxo-3-phenethyl-3,9-diaza-bicyclo[3.3.1]nonane-9-carboxylic acid benzyl ester

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