6-Chloro-chroman-3-ylamine hydrochloride

Base Information

Chemical Name:6-Chloro-chroman-3-ylamine hydrochloride
CAS No.:54444-99-4
Molecular Formula:C9H11Cl2NO
Molecular Weight:220.09574
Hs Code.:
DSSTox Substance ID:DTXSID20484762
Mol file:54444-99-4.mol

Synonyms:54444-99-4;6-CHLORO-CHROMAN-3-YLAMINE HYDROCHLORIDE;6-Chlorochroman-3-amine hydrochloride;6-chloro-3,4-dihydro-2H-chromen-3-amine;hydrochloride;6-CHLORO-3,4-DIHYDRO-2H-1-BENZOPYRAN-3-AMINE HYDROCHLORIDE;6-chlorochroman-3-ylamine HCl;SCHEMBL21811006;DTXSID20484762;MFCD09026814;WS-02307;CS-0343001;6-chlorochroman-3-aminehydrochloride?SFC=3:1?;E72383;6-Chloro-3,4-dihydro-2H-1-benzopyran-3-amine--hydrogen chloride (1/1)

Suppliers and Price of 6-Chloro-chroman-3-ylamine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-CHLORO-CHROMAN-3-YLAMINE HYDROCHLORIDE 95.00%
5MG
$ 497.42

Total 6 raw suppliers

Chemical Property of 6-Chloro-chroman-3-ylamine hydrochloride

Chemical Property:

PSA：35.25000
LogP:3.10450
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:219.0217694
Heavy Atom Count:13
Complexity:165

Purity/Quality:

99% ^*data from raw suppliers

6-CHLORO-CHROMAN-3-YLAMINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(COC2=C1C=C(C=C2)Cl)N.Cl

Technology Process of 6-Chloro-chroman-3-ylamine hydrochloride

There total 3 articles about 6-Chloro-chroman-3-ylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 916223-22-8
(R)-N-(6-chlorochroman-3-yl)-2,2,2-trifluoroacetamide

: 54444-99-4
(R)-6-chlorochroman-3-amine hydrochloride

Guidance literature:: (R)-N-(6-chlorochroman-3-yl)-2,2,2-trifluoroacetamide; With water; sodium hydroxide; In chloroform; at 20 ℃; for 17h;

With hydrogenchloride; In ethyl acetate;

Reference yield:

: 18518-71-3,211506-59-1,211506-60-4
(R)-chroman-3-amine hydrochloride

: 54444-99-4
(R)-6-chlorochroman-3-amine hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 2 h / 20 °C

2: N-chloro-succinimide / acetonitrile / 6 h / 70 °C

3: water; sodium hydroxide / chloroform / 17 h / 20 °C

With N-chloro-succinimide; water; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In dichloromethane; chloroform; acetonitrile;

Reference yield:

: 916223-21-7
(R)-N-(chroman-3-yl)-2,2,2-trifluoroacetamide

: 54444-99-4
(R)-6-chlorochroman-3-amine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: N-chloro-succinimide / acetonitrile / 6 h / 70 °C

2: water; sodium hydroxide / chloroform / 17 h / 20 °C

With N-chloro-succinimide; water; sodium hydroxide; In chloroform; acetonitrile;