1H-Imidazole-2-carboxylicacid,1-methyl-4-[[(1-methyl-1H-imidazol-2-

Base Information

Chemical Name:1H-Imidazole-2-carboxylicacid,1-methyl-4-[[(1-methyl-1H-imidazol-2-
CAS No.:464892-44-2
Molecular Formula:C10H11N5O3
Molecular Weight:249.229
Hs Code.:
Mol file:464892-44-2.mol

Synonyms:1H-Imidazole-2-carboxylicacid,1-methyl-4-[[(1-methyl-1H-imidazol-2-

Suppliers and Price of 1H-Imidazole-2-carboxylicacid,1-methyl-4-[[(1-methyl-1H-imidazol-2-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of 1H-Imidazole-2-carboxylicacid,1-methyl-4-[[(1-methyl-1H-imidazol-2-

Chemical Property:

PKA:0.92±0.32(Predicted)
PSA：102.04000
Density:1.53±0.1 g/cm3(Predicted)
LogP:0.17710

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Imidazole-2-carboxylicacid,1-methyl-4-[[(1-methyl-1H-imidazol-2-

There total 5 articles about 1H-Imidazole-2-carboxylicacid,1-methyl-4-[[(1-methyl-1H-imidazol-2- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1238707-21-5
tert-butyl 4-(1-methylimidazole-2-carboxamido)-1-methylimidazole-2-carboxylate

: 464892-44-2
4-(1-methylimidazole-2-carboxamido)-1-methylimidazole-2-carboxylic acid

Guidance literature:: With titanium tetrachloride; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/ol1013262

Reference yield: 82.0%

: 849665-11-8
methyl 4-(N-methyl-1H-imidazole-2-carboxamido)-N-methyl-1H-imidazole-2-carboxylate

: 464892-44-2
4-(1-methylimidazole-2-carboxamido)-1-methylimidazole-2-carboxylic acid

Guidance literature:: methyl 4-(N-methyl-1H-imidazole-2-carboxamido)-N-methyl-1H-imidazole-2-carboxylate; With sodium hydroxide; In methanol; water; at 50 ℃; for 12h;

With hydrogenchloride; In water; at 0 ℃; pH=2;

Reference yield:

: 162085-97-4
methyl 4-amino-1-methyl-1H-imidazole-2-carboxylate

: 464892-44-2
4-(1-methylimidazole-2-carboxamido)-1-methylimidazole-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 0.72 g / triethylamine / ethyl acetate / 6 h

2: LiOH / tetrahydrofuran; methanol / 2 h / 60 °C

With lithium hydroxide; triethylamine; In tetrahydrofuran; methanol; ethyl acetate;
DOI:10.1002/chem.200601486