(2R)-1-tert-butyl-2-[(2R)-1-tert-butylphospholan-2-yl]phospholane

Base Information

Chemical Name:(2R)-1-tert-butyl-2-[(2R)-1-tert-butylphospholan-2-yl]phospholane
CAS No.:470480-32-1
Molecular Formula:C16H32P2
Molecular Weight:286.37
Hs Code.:
DSSTox Substance ID:DTXSID80587324
Nikkaji Number:J1.836.368B
Wikidata:Q82479726
Mol file:470480-32-1.mol

Synonyms:470480-32-1;(2R)-1-tert-butyl-2-[(2R)-1-tert-butylphospholan-2-yl]phospholane;(2R,2'R)-1,1'-di-tert-butyl-2,2'-biphospholane;(1S,1S',2R,2R')-(+)-1,1'-DI-T-BUTYL-[2,2']-DIPHOSPHOLANE;SCHEMBL14823194;DTXSID80587324;SJNUZTRUIDRSJK-JDPPGYRCSA-N;(1S,1S,2R,2R)-(+)-1,1-Di-t-butyl-[2,2]-diphospholane

Suppliers and Price of (2R)-1-tert-butyl-2-[(2R)-1-tert-butylphospholan-2-yl]phospholane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(1S,1S',2R,2R')-(+)-1,1'-DI-T-BUTYL-[2,2']-DIPHOSPHOLANE 95.00%
500MG
$ 1172.73

American Custom Chemicals Corporation
(1S,1S',2R,2R')-(+)-1,1'-DI-T-BUTYL-[2,2']-DIPHOSPHOLANE 95.00%
100MG
$ 711.28

Total 9 raw suppliers

Chemical Property of (2R)-1-tert-butyl-2-[(2R)-1-tert-butylphospholan-2-yl]phospholane

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:60-65 °C
Boiling Point:353.584°C at 760 mmHg
Flash Point:176.043°C
PSA：27.18000
LogP:5.87200
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:3
Exact Mass:286.19792502
Heavy Atom Count:18
Complexity:255

Purity/Quality:

98%,99%, ^*data from raw suppliers

(1S,1S',2R,2R')-(+)-1,1'-DI-T-BUTYL-[2,2']-DIPHOSPHOLANE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)P1CCCC1C2CCCP2C(C)(C)C
Isomeric SMILES:CC(C)(C)P1CCC[C@@H]1[C@H]2CCCP2C(C)(C)C
Uses Chiral Quest Phosphine Ligands for Asymmetric HydrogenationCatalytic ligand used in:Preparation of α-borono-substituted alkylarenes by asymmetric hydroboration of styrenes catalyzed by copper(I)Enantioselective synthesis of spiroindane di-Me acetic acid via hydrogenation of spiroindane di-Me acetic acid catalyzed by Ru(II)Asymmetric γ-addition of thiols to allenoatesRhodium-catalyzed intermolecular enantioselective hydroacylation of alkynes to give alpha- and beta-substituted unsaturated ketones by kinetic resolutionStereoselective preparation of β-amino nitriles via rhodium-catalyzed asymmetric hydrogenation of amino acrylonitriles

Technology Process of (2R)-1-tert-butyl-2-[(2R)-1-tert-butylphospholan-2-yl]phospholane

There total 2 articles about (2R)-1-tert-butyl-2-[(2R)-1-tert-butylphospholan-2-yl]phospholane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: (1R,2R,1'R,2'R)-1,1'-Di-tert-butyl-[2,2']biphospholanyl 1,1'-disulfide

: 470480-32-1
(S,S',R,R')-tangphos

Guidance literature:: (1R,2R,1'R,2'R)-1,1'-Di-tert-butyl-[2,2']biphospholanyl 1,1'-disulfide; With hexachlorodisilane; In benzene; for 4h; Heating;

With sodium hydroxide; In water; benzene; at 60 ℃;
DOI:10.1002/1521-3773(20020503)41:9<1612::AID-ANIE1612>3.0.CO;2-H

Reference yield:

: 470480-33-2
1-tert-butyl-phospholane 1-sulfide

: 470480-32-1
(S,S',R,R')-tangphos

Guidance literature:: Multi-step reaction with 2 steps

1.1: 20 percent / n-BuLi; (-)-sparteine; CuCl₂

2.1: hexachlorodisilane / benzene / 4 h / Heating

2.2: 88 percent / NaOH / benzene; H₂O / 60 °C

With n-butyllithium; hexachlorodisilane; copper dichloride; (-)-sparteine; In benzene;
DOI:10.1002/1521-3773(20020503)41:9<1612::AID-ANIE1612>3.0.CO;2-H