D-Ribofuranoside, methyl 5-deoxy-5-[(1-oxo-2-propenyl)amino]- (9CI)

Base Information

Chemical Name:D-Ribofuranoside, methyl 5-deoxy-5-[(1-oxo-2-propenyl)amino]- (9CI)
CAS No.:474105-04-9
Molecular Formula:C9H15NO5
Molecular Weight:217.2191
Hs Code.:
Mol file:474105-04-9.mol

Synonyms:D-Ribofuranoside, methyl 5-deoxy-5-[(1-oxo-2-propenyl)amino]- (9CI)

Suppliers and Price of D-Ribofuranoside, methyl 5-deoxy-5-[(1-oxo-2-propenyl)amino]- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of D-Ribofuranoside, methyl 5-deoxy-5-[(1-oxo-2-propenyl)amino]- (9CI)

Chemical Property:

PSA：88.02000
LogP:-1.22740

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Technology Process of D-Ribofuranoside, methyl 5-deoxy-5-[(1-oxo-2-propenyl)amino]- (9CI)

There total 4 articles about D-Ribofuranoside, methyl 5-deoxy-5-[(1-oxo-2-propenyl)amino]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.1%

: 814-68-6,25189-84-8
acryloyl chloride

: 474105-03-8
(2R,3S,4R)-2-Aminomethyl-5-methoxy-tetrahydro-furan-3,4-diol

: 474105-04-9
N-((2R,3S,4R)-3,4-Dihydroxy-5-methoxy-tetrahydro-furan-2-ylmethyl)-acrylamide

Guidance literature:: In tetrahydrofuran; at 0 ℃; for 11h;
DOI:10.1016/S0040-4039(02)01123-1

Reference yield:

: 1824-96-0,1824-97-1,3795-68-4,3795-69-5,4229-54-3,5531-18-0,7473-45-2,13039-63-9,13039-64-0,13039-65-1,13039-67-3,22416-73-5,22861-09-2,25129-51-5,52485-92-4,52689-55-1,52689-56-2,56607-40-0,72880-70-7,79083-42-4,86782-30-1,86782-31-2,89615-03-2,89673-67-6,89707-99-3,102045-32-9,135910-17-7
methyl ribofuranoside

: 474105-04-9
N-((2R,3S,4R)-3,4-Dihydroxy-5-methoxy-tetrahydro-furan-2-ylmethyl)-acrylamide

Guidance literature:: Multi-step reaction with 4 steps

1: 60.9 percent / PPh₃; I₂; pyridine / dioxane / 24 h / 25 °C

2: 97.8 percent / NaN₃ / dimethylformamide / 24 h / 60 °C

3: 64.4 percent / PPh₃ / tetrahydrofuran; H₂O / 24 h / 25 °C

4: 47.1 percent / tetrahydrofuran / 11 h / 0 °C

With pyridine; sodium azide; iodine; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(02)01123-1

Reference yield:

: 256239-89-1
methyl 5-deoxy-5-iodo-αlpha;/β-D-riboside

: 474105-04-9
N-((2R,3S,4R)-3,4-Dihydroxy-5-methoxy-tetrahydro-furan-2-ylmethyl)-acrylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 97.8 percent / NaN₃ / dimethylformamide / 24 h / 60 °C

2: 64.4 percent / PPh₃ / tetrahydrofuran; H₂O / 24 h / 25 °C

3: 47.1 percent / tetrahydrofuran / 11 h / 0 °C

With sodium azide; triphenylphosphine; In tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(02)01123-1