(2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine

Base Information

Chemical Name:(2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine
CAS No.:475160-61-3
Molecular Formula:C10H20N2
Molecular Weight:168.28
Hs Code.:
DSSTox Substance ID:DTXSID901180925
Nikkaji Number:J1.793.289F
Mol file:475160-61-3.mol

Synonyms:475160-61-3;(2R,4S,5R)-2-AMINOMETHYL-5-ETHYLQUINUCLIDINE;((2R,4S,5R)-5-Ethylquinuclidin-2-yl)methanamine;starbld0001707;DTXSID901180925;AKOS025295355;(1S,2R,4S,5R)-5-Ethyl-1-azabicyclo[2.2.2]octane-2-methanamine;(2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine, >=95.0% (GC)

Suppliers and Price of (2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine ≥95.0% (GC)
100mg-f
$ 106.00

American Custom Chemicals Corporation
(2R,4S,5R)-2-AMINOMETHYL-5-ETHYLQUINUCLIDINE 95.00%
1G
$ 1143.02

American Custom Chemicals Corporation
(2R,4S,5R)-2-AMINOMETHYL-5-ETHYLQUINUCLIDINE 95.00%
500MG
$ 1001.73

American Custom Chemicals Corporation
(2R,4S,5R)-2-AMINOMETHYL-5-ETHYLQUINUCLIDINE 95.00%
250MG
$ 719.17

American Custom Chemicals Corporation
(2R,4S,5R)-2-AMINOMETHYL-5-ETHYLQUINUCLIDINE 95.00%
100MG
$ 659.49

Total 1 raw suppliers

Chemical Property of (2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine

Chemical Property:

Vapor Pressure:0.113mmHg at 25°C
Refractive Index:n20/D 1.497
Boiling Point:220.4°C at 760 mmHg
Flash Point:83.5°C
PSA：29.26000
Density:0.99g/cm³
LogP:1.70370
Storage Temp.:2-8°C
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:168.162648646
Heavy Atom Count:12
Complexity:158

Purity/Quality:

97% ^*data from raw suppliers

(2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine ≥95.0% (GC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-37/38-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1CN2CCC1CC2CN
Isomeric SMILES:CC[C@H]1CN2CC[C@H]1C[C@@H]2CN

Technology Process of (2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine

There total 3 articles about (2R,4S,5R)-2-Aminomethyl-5-ethylquinuclidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 290817-91-3
(1S,2R,4S,5R)-2-(aminomethyl)-5-vinyl-1-azabicyclo-[2.2.2]octane

: 475160-61-3
(1S,2R,4S,5R)-2-(aminomethyl)-5-ethyl-1-azabicyclo[2.2.2]octane

Guidance literature:: With hydrogen; palladium on activated charcoal; In tetrahydrofuran; at 20 ℃; for 8h; under 750.06 Torr;
DOI:10.1016/S0957-4166(02)00320-8

Reference yield:

: 219794-81-7
(1S,2R,4S,5R)-2-(hydroxymethyl)-5-ethyl-1-azabicyclo[2.2.2]octane

: 475160-61-3
(1S,2R,4S,5R)-2-(aminomethyl)-5-ethyl-1-azabicyclo[2.2.2]octane

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / (C₆H₅)3P; diethyl azodicarboxylate; HN₃ / 2.5 h / Heating

2: 54 percent / H₂ / Pd/C

With tris-(2-chloro-ethyl)-amine; hydrogen; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal;
DOI:10.1016/S0957-4166(02)00320-8