[2,3-Dihydroxy-4-(4-methylphenyl)sulfonyloxybutyl] 4-methylbenzenesulfonate

Base Information

Chemical Name:[2,3-Dihydroxy-4-(4-methylphenyl)sulfonyloxybutyl] 4-methylbenzenesulfonate
CAS No.:57495-46-2
Molecular Formula:C18H22 O8 S2
Molecular Weight:430.5
Hs Code.:
NSC Number:126574,123094,297839,260675
DSSTox Substance ID:DTXSID50964860
Mol file:57495-46-2.mol

Synonyms:50623-73-9;[2,3-dihydroxy-4-(4-methylphenyl)sulfonyloxybutyl] 4-methylbenzenesulfonate;NSC260675;68138-99-8;SCHEMBL1730532;DTXSID50964860;NSC123094;NSC126574;NSC297839;NSC-123094;NSC-126574;NSC-260675;NSC-297839;FT-0639916;2,3-Dihydroxybutane-1,4-diyl bis(4-methylbenzene-1-sulfonate)

Suppliers and Price of [2,3-Dihydroxy-4-(4-methylphenyl)sulfonyloxybutyl] 4-methylbenzenesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
L-Threitol-1,4-ditosylate
2.5g
$ 580.00

American Custom Chemicals Corporation
(-)-1 4-DI-ORTHO-TOSYL-L-THREITOL 95.00%
5MG
$ 498.58

AHH
(-)-1 4-Di-o-tosyl-L-threitol 98%
10g
$ 435.00

Total 5 raw suppliers

Chemical Property of [2,3-Dihydroxy-4-(4-methylphenyl)sulfonyloxybutyl] 4-methylbenzenesulfonate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:657.6°Cat760mmHg
Flash Point:351.5°C
PSA：143.96000
Density:1.397g/cm³
LogP:3.29760
Solubility.:DCM, Ethyl Acetate
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:9
Exact Mass:430.07561000
Heavy Atom Count:28
Complexity:603

Purity/Quality:

99% ^*data from raw suppliers

L-Threitol-1,4-ditosylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)OCC(C(COS(=O)(=O)C2=CC=C(C=C2)C)O)O
Uses L-Threitol-1,4-ditosylate is a tosyl protected L-Threitol (T400000), an intermediate used to synthesize novel aza-sugar-based metalloproteinase MMP/ADAM inhibitors.

Technology Process of [2,3-Dihydroxy-4-(4-methylphenyl)sulfonyloxybutyl] 4-methylbenzenesulfonate

There total 3 articles about [2,3-Dihydroxy-4-(4-methylphenyl)sulfonyloxybutyl] 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 37002-45-2
(4S,5S)-2,2-dimethyl-4,5-bis(p-toluenesulfonyloxymethyl)-1,3-dioxolan

: 57495-46-2,68138-99-8
(2S,3S)-butane-1,4-diol bis[4-methylbenzenesulfonate]

Guidance literature:: With hydrogenchloride; In methanol; for 5h; Heating;
DOI:10.1002/hc.20076

Reference yield:

: 57495-46-2,68138-99-8
(2S,3S)-butane-1,4-diol bis[4-methylbenzenesulfonate]

Guidance literature:: With hydrogenchloride;
DOI:10.1002/hlca.19770600202

Reference yield:

: 98-59-9
p-toluenesulfonyl chloride

: 57495-46-2,68138-99-8
(2S,3S)-butane-1,4-diol bis[4-methylbenzenesulfonate]

Guidance literature:: Multi-step reaction with 2 steps

1.1: pyridine / -10 °C

1.2: 80 percent / pyridine / 20 °C

2.1: 100 percent / 0.5 N hydrochloric acid / methanol / 5 h / Heating

With hydrogenchloride; In pyridine; methanol;
DOI:10.1002/hc.20076