Benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate

Base Information

Chemical Name:Benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate
CAS No.:481001-67-6
Molecular Formula:C17H17NO2
Molecular Weight:267.32
Hs Code.:2933499090
DSSTox Substance ID:DTXSID30375238
Mol file:481001-67-6.mol

Synonyms:benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate;481001-67-6;1,2,3,4-Tetrahydro-quinoline-2-carboxylic acid benzyl ester;1,2,3,4-Tetrahydro-quinoline-2-carboxylic acidbenzyl ester;SCHEMBL6395940;DTXSID30375238;MFCD03426410;AKOS015897023;FT-0655465;benzyl1,2,3,4-tetrahydroquinoline-2-carboxylate;Q-103203;1,2,3,4-TETRAHYDROQUINOLINE-2-CARBOXYLIC ACIDBENZYL ESTER

Suppliers and Price of Benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
1,2,3,4-Tetrahydro-quinoline-2-carboxylicacidbenzylester 95%
1g
$ 636.00

American Custom Chemicals Corporation
1,2,3,4-TETRAHYDRO-QUINOLINE-2-CARBOXYLIC ACID BENZYL ESTER 95.00%
5G
$ 1342.27

Alichem
Benzyl1,2,3,4-tetrahydroquinoline-2-carboxylate
1g
$ 720.80

Total 15 raw suppliers

Chemical Property of Benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate

Chemical Property:

Vapor Pressure:1.82E-07mmHg at 25°C
Refractive Index:1.584
Boiling Point:426.1°Cat760mmHg
Flash Point:211.5°C
PSA：38.33000
Density:1.159g/cm³
LogP:3.29470
Storage Temp.:2-8°C
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:267.125928785
Heavy Atom Count:20
Complexity:325

Purity/Quality:

97% ^*data from raw suppliers

1,2,3,4-Tetrahydro-quinoline-2-carboxylicacidbenzylester 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=CC=CC=C2NC1C(=O)OCC3=CC=CC=C3

Technology Process of Benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate

There total 12 articles about Benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: benzyl 4-(2-aminophenyl)-2-diazobutanoate

: 481001-67-6
(-)-benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate

: 481001-67-6
benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate

Guidance literature:: With C₃₅H₃₀N₂O₂; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate; copper dichloride; In dichloromethane; at 25 ℃; for 0.5h; Overall yield = 81 %; enantioselective reaction; Schlenk technique;
DOI:10.1002/adsc.201600390

Reference yield:

: benzyl 4-(2-aminophenyl)-2-diazobutanoate

: 481001-67-6
(-)-benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate

: 481001-67-6
benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate

Guidance literature:: With C₃₅H₃₀N₂O₂; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate; copper dichloride; In dichloromethane; at 25 ℃; for 0.5h; Overall yield = 81 %; enantioselective reaction; Schlenk technique;
DOI:10.1002/adsc.201600390

Reference yield:

: benzyl 2-acetyl-4-(2-(1,3-dioxoisoindolin-2-yl)phenyl)butanoate

: 481001-67-6
(-)-benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate

: 481001-67-6
benzyl 1,2,3,4-tetrahydroquinoline-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene; Methanesulfonyl azide / dichloromethane / 1 h / 20 °C / Schlenk technique

2: hydrazine hydrate / methanol / 20 °C / Schlenk technique

3: copper dichloride; C₃₅H₃₀N₂O₂; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate / dichloromethane / 0.5 h / 25 °C / Schlenk technique

With C₃₅H₃₀N₂O₂; hydrazine hydrate; 1,8-diazabicyclo[5.4.0]undec-7-ene; sodium tetrakis[(3,5-di-trifluoromethyl)phenyl]borate; Methanesulfonyl azide; copper dichloride; In methanol; dichloromethane;
DOI:10.1002/adsc.201600390