4-(2-Thienyl)-2,3-dihydro-1H-1,5-benzodiazepine

Base Information

Chemical Name:4-(2-Thienyl)-2,3-dihydro-1H-1,5-benzodiazepine
CAS No.:497178-55-9
Molecular Formula:C13H12N2S
Molecular Weight:228.31
Hs Code.:2934999090
DSSTox Substance ID:DTXSID60378015
Mol file:497178-55-9.mol

Synonyms:497178-55-9;4-(2-THIENYL)-2,3-DIHYDRO-1H-1,5-BENZODIAZEPINE;4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepine;4-thiophen-2-yl-2,3-dihydro-1H-1,5-benzodiazepine;MFCD06245379;DTXSID60378015;BBL100536;STL554330;AKOS005254258;MS-20033;2,3-Dihydro-4-thien-2-yl-1H-1,5-benzodiazepine;(E)-4-(thiophen-2-yl)-2,3-dihydro-1H-benzo[b][1,4]diazepine

Suppliers and Price of 4-(2-Thienyl)-2,3-dihydro-1H-1,5-benzodiazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepine
10mg
$ 60.00

American Custom Chemicals Corporation
4-(2-THIENYL)-2,3-DIHYDRO-1H-1,5-BENZODIAZEPINE 95.00%
500MG
$ 842.36

Total 6 raw suppliers

Chemical Property of 4-(2-Thienyl)-2,3-dihydro-1H-1,5-benzodiazepine

Chemical Property:

Vapor Pressure:5.06E-06mmHg at 25°C
Refractive Index:1.687
Boiling Point:381.5°Cat760mmHg
Flash Point:184.5°C
PSA：52.63000
Density:1.26g/cm³
LogP:3.25810
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:228.07211956
Heavy Atom Count:16
Complexity:277

Purity/Quality:

NLT 98% ^*data from raw suppliers

4-(Thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNC2=CC=CC=C2N=C1C3=CC=CS3

Technology Process of 4-(2-Thienyl)-2,3-dihydro-1H-1,5-benzodiazepine

There total 2 articles about 4-(2-Thienyl)-2,3-dihydro-1H-1,5-benzodiazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 5424-47-5
3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one hydrochloride

: 95-54-5
1,2-diamino-benzene

: 497178-55-9
4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepine

Guidance literature:: In ethanol; for 0.5h; Reflux;

Reference yield:

: 88-15-3,97511-16-5
2-Acetylthiophene

: 497178-55-9
4-(thiophen-2-yl)-2,3-dihydro-1H-1,5-benzodiazepine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / ethanol / 8 h / Reflux

2: ethanol / 0.5 h / Reflux

With hydrogenchloride; In ethanol; 1: |Mannich Aminomethylation;