3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline

Base Information

Chemical Name:3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline
CAS No.:537705-06-9
Molecular Formula:C13H14N2O
Molecular Weight:214.267
Hs Code.:2933399090
DSSTox Substance ID:DTXSID00465433
Wikidata:Q82291376
Mol file:537705-06-9.mol

Synonyms:537705-06-9;3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline;3-METHYL-4-(6-METHYL-PYRIDIN-3-YLOXY)-PHENYLAMINE;3-Methyl-4-(6-methylpyridin-3-yl)oxyaniline;3-METHYL-4-(6-METHYLPYRIDIN-3-YLOXY)ANILINE;3-methyl-4-[(6-methylpyridin-3-yl)oxy]aniline;SCHEMBL215985;DTXSID00465433;GBMQBBQKWXOOJZ-UHFFFAOYSA-N;AR2453;MFCD06657266;AKOS011352336;CS-0038054;4-(6-methylpyridin-3-yloxy)-3-methylbenzenamine;3-methyl-4-(6-methyl-pyridine-3-yloxy)-phenylamine;A1-48719;3-METHYL-4-[(6-METHYL-3-PYRIDINYL)OXY]ANILINE

Suppliers and Price of 3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Methyl-4-(6-methylpyridin-3-yloxy)aniline
250mg
$ 450.00

Labseeker
3-methyl-4-(6-methyl-pyridin-3-yloxy)-phenylamine 95
50g
$ 3025.00

Crysdot
3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline 95+%
1g
$ 377.00

Chemenu
3-methyl-4-((6-methylpyridin-3-yl)oxy)aniline 95%
1g
$ 356.00

American Custom Chemicals Corporation
3-METHYL-4-(6-METHYL-PYRIDIN-3-YLOXY)-PHENYLAMINE 95.00%
5G
$ 2595.29

American Custom Chemicals Corporation
3-METHYL-4-(6-METHYL-PYRIDIN-3-YLOXY)-PHENYLAMINE 95.00%
1G
$ 1055.09

American Custom Chemicals Corporation
3-METHYL-4-(6-METHYL-PYRIDIN-3-YLOXY)-PHENYLAMINE 95.00%
100MG
$ 648.83

Alichem
3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline
1g
$ 335.72

AK Scientific
3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline
250mg
$ 239.00

AK Scientific
3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline
1g
$ 623.00

Total 9 raw suppliers

Chemical Property of 3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline

Chemical Property:

Boiling Point:349.9±42.0 °C(Predicted)
PKA:4.65±0.10(Predicted)
PSA：48.14000
Density:1.139±0.06 g/cm3(Predicted)
LogP:3.65410
Storage Temp.:2-8°C
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:214.110613074
Heavy Atom Count:16
Complexity:222

Purity/Quality:

97% ^*data from raw suppliers

3-Methyl-4-(6-methylpyridin-3-yloxy)aniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=C(C=C1)OC2=C(C=C(C=C2)N)C
Uses 3-Methyl-4-(6-methylpyridin-3-yloxy)aniline is a versatile reactant used in the preparation of alkoxypyrazolopyrimidines with EGFR and erbB2 receptor tyrosine kinase inhibitory activity.

Technology Process of 3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline

There total 5 articles about 3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 697299-78-8
2-methyl-5-(2-methyl-4-nitrophenoxy)pyridine

: 537705-06-9
3-(2-methyl-4-aminophenoxy)-6-methylpyridine

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; for 24h; under 760.051 Torr;

Reference yield: 81.0%

: 537705-06-9
3-(2-methyl-4-aminophenoxy)-6-methylpyridine

Guidance literature:

Reference yield:

: 1121-78-4
5-Hydroxy-2-methylpyridine

: 537705-06-9
3-(2-methyl-4-aminophenoxy)-6-methylpyridine

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / N,N-dimethyl-formamide / 4 h / 110 °C

2: hydrogen / palladium 10% on activated carbon / methanol / 24 h / 3102.97 Torr

With hydrogen; caesium carbonate; palladium 10% on activated carbon; In methanol; N,N-dimethyl-formamide;