6,8-DIMETHOXY-4-METHYLQUINOLINE

Base Information

• Chemical Name: 6,8-DIMETHOXY-4-METHYLQUINOLINE
• CAS No.: 51049-14-0
• Molecular Formula: C₁₂H₁₃NO₂
• Molecular Weight: 203.241
• Hs Code.: 2933499090
• Mol file: 51049-14-0.mol

Synonyms:6,8-DIMETHOXY-4-METHYLQUINOLINE;Dimethoxymethylquinoline;6,8-DIMETHOXY-4-METHYLQUINOLINE HYDRATE;6,8-DIMETHOXY-4-METHYLQUINOLINE 98+%

Chemical Property of 6,8-DIMETHOXY-4-METHYLQUINOLINE

Chemical Property:

• Melting Point: 65°C
• Boiling Point: 346.4±37.0 °C(Predicted)
• PKA: 4.00±0.33(Predicted)
• PSA: 31.35000
• Density: 1.122±0.06 g/cm3(Predicted)
• LogP: 2.56040

Purity/Quality:

98%,99%, ^*data from raw suppliers

6,8-Dimethoxy-4-methylquinoline ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 26-36/37/39-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6,8-DIMETHOXY-4-METHYLQUINOLINE

There total 1 articles about 6,8-DIMETHOXY-4-METHYLQUINOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

4-bromobut-1-yne (38771-21-0) + 2,4-Dimethoxyaniline (2735-04-8,161687-55-4) → 6,8-dimethoxy-4-methylquinoline (51049-14-0)

Guidance literature:

With sodium tetrachloroaurate(III) dihyrate; In ethanol; at 70 ℃; for 24h;

DOI:10.1016/j.tetlet.2011.07.115

Reference yield:

6,8-dimethoxy-4-methylquinoline (51049-14-0) + 2-(cyclohexylsulfonyl)-1-phenylpropan-1-one → 2-cyclohexyl-6,8-dimethoxy-4-methylquinoline

Guidance literature:

With trifluoroacetic acid; In acetone; at 80 ℃; Inert atmosphere; Schlenk technique; UV-irradiation;

DOI:10.1021/jacs.7b08685

upstream raw materials:

4-bromobut-1-yne

2,4-Dimethoxyaniline

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