ethyl 3-(2,4-dioxo-1H-pyrimidin-5-yl)prop-2-enoate

Base Information

Chemical Name:ethyl 3-(2,4-dioxo-1H-pyrimidin-5-yl)prop-2-enoate
CAS No.:55520-60-0
Molecular Formula:C₉H₁₀N₂O₄
Molecular Weight:210.189
Hs Code.:
DSSTox Substance ID:DTXSID70307952
Mol file:55520-60-0.mol

Synonyms:55520-60-0;DTXSID70307952;NCI60_001644

Suppliers and Price of ethyl 3-(2,4-dioxo-1H-pyrimidin-5-yl)prop-2-enoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(E)-5-ETHOXYCARBONYLVINYL URACIL 95.00%
5MG
$ 498.03

Total 1 raw suppliers

Chemical Property of ethyl 3-(2,4-dioxo-1H-pyrimidin-5-yl)prop-2-enoate

Chemical Property:

PSA：92.02000
LogP:-0.36050
XLogP3:-0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:210.06405680
Heavy Atom Count:15
Complexity:357

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

(E)-5-ETHOXYCARBONYLVINYL URACIL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C=CC1=CNC(=O)NC1=O

Technology Process of ethyl 3-(2,4-dioxo-1H-pyrimidin-5-yl)prop-2-enoate

There total 2 articles about ethyl 3-(2,4-dioxo-1H-pyrimidin-5-yl)prop-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 1195-08-0
2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde

: 1099-45-2
ethyl (triphenylphosphoranylidene)acetate

: 55520-59-7
ethyl-(Z)-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate

: 55520-60-0
ethyl-(E)-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate

Guidance literature:: In N,N-dimethyl-formamide; for 16h; Ambient temperature;

Reference yield:

: 55520-60-0
ethyl-(E)-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate

Guidance literature:: 5-Formyl-uracil (5), Ph3P=CH-COOC2H5;
DOI:10.1021/jm00223a042

Reference yield:

: 2-deoxy-3,5-di-O-p-toluoyl-α-D-ribofuranosyl chloride

: 55520-60-0
ethyl-(E)-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylate

: ethyl-(E)-3-<1-(2-deoxy-3',5'-di-p-toluoyl-β-D-erythro-pentofuranosyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl>acrylate

Guidance literature:: With 1,1,1,3,3,3-hexamethyl-disilazane; trimethylsilyl trifluoromethanesulfonate; Yield given. Multistep reaction; 1.) pyridine, reflux, 2 h; 2.) chloroform, room temp.;