Carboxyphosphamide Benzyl Ester

Base Information

• Chemical Name: Carboxyphosphamide Benzyl Ester
• CAS No.: 37979-67-2
• Molecular Formula: C₁₄H₂₁Cl₂N₂O₄P
• Molecular Weight: 383.212
• Hs Code.: 2931900090
• Mol file: 37979-67-2.mol

Synonyms:benzyl 3-[amino-[bis(2-chloroethyl)amino]phosphoryl]oxypropanoate;

Chemical Property of Carboxyphosphamide Benzyl Ester

Chemical Property:

• Vapor Pressure: 3.15E-10mmHg at 25°C
• Boiling Point: 502.5°C at 760 mmHg
• PKA: 0.93±0.70(Predicted)
• Flash Point: 257.7°C
• PSA: 91.67000
• Density: 1.326g/cm³
• LogP: 3.68320
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

CarboxyphosphamideBenzylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carboxyphosphamide Benzyl Ester

There total 2 articles about Carboxyphosphamide Benzyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C14H19Cl3NO4P (37960-23-9) → C14H21Cl2N2O4P (37979-67-2)

Guidance literature:

With ammonia; In dichloromethane;

DOI:10.1248/cpb.20.1612

Reference yield:

benzyl 2-O-(phosphorodichloro)propionate (84681-46-9) → C14H21Cl2N2O4P (37979-67-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / diethyl ether

2: NH₃ / CH₂Cl₂

With ammonia; triethylamine; In diethyl ether; dichloromethane;

DOI:10.1248/cpb.20.1612

Reference yield:

C14H21Cl2N2O4P (37979-67-2) → Carboxyphosphamide (22788-18-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1248/cpb.20.1612

upstream raw materials:

C₁₄H₁₉Cl₃NO₄P

benzyl 2-O-(phosphorodichloro)propionate

Downstream raw materials:

Carboxyphosphamide

Refernces