3-(5-Chloro-2-methoxyphenyl)-1,2-oxazol-5-amine

Base Information

Chemical Name:3-(5-Chloro-2-methoxyphenyl)-1,2-oxazol-5-amine
CAS No.:501116-39-8
Molecular Formula:C₁₀H₉ClN₂O₂
Molecular Weight:224.647
Hs Code.:
DSSTox Substance ID:DTXSID80394671
Wikidata:Q82194205
Mol file:501116-39-8.mol

Synonyms:501116-39-8;3-(5-chloro-2-methoxyphenyl)-1,2-oxazol-5-amine;3-(5-CHLORO-2-METHOXY-PHENYL)-ISOXAZOL-5-YLAMINE;3-(5-Chloro-2-methoxyphenyl)isoxazol-5-amine;ETHYL2-IODOBENZOATE;SCHEMBL23292482;DTXSID80394671;AKOS000262257;CS-0238503;3-(5-chloro-2-methoxyphenyl)isoxazol-5-ylamine;EN300-1964555

Suppliers and Price of 3-(5-Chloro-2-methoxyphenyl)-1,2-oxazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
3-(5-Chloro-2-methoxy-phenyl)-isoxazol-5-ylamine 95
10g
$ 3667.00

American Custom Chemicals Corporation
3-(5-CHLORO-2-METHOXY-PHENYL)-ISOXAZOL-5-YLAMINE 95.00%
5MG
$ 502.10

Total 3 raw suppliers

Chemical Property of 3-(5-Chloro-2-methoxyphenyl)-1,2-oxazol-5-amine

Chemical Property:

PSA：61.28000
LogP:3.16700
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:224.0352552
Heavy Atom Count:15
Complexity:218

Purity/Quality:

99% ^*data from raw suppliers

3-(5-Chloro-2-methoxy-phenyl)-isoxazol-5-ylamine 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)Cl)C2=NOC(=C2)N

Technology Process of 3-(5-Chloro-2-methoxyphenyl)-1,2-oxazol-5-amine

There total 1 articles about 3-(5-Chloro-2-methoxyphenyl)-1,2-oxazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 33924-48-0
methyl 5-chloro-2-methoxybenzoate

: 5-(5-chloro-2-methoxyphenyl)isoxazol-3-amine

: 501116-39-8
3-(5-chloro-2-methoxyphenyl)isoxazol-5-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: diisopropylamine; n-butyllithium / hexane; tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

1.2: 0.67 h / -78 °C

2.1: hydroxylamine hydrochloride; sodium hydroxide / ethanol; water / 80 °C

With n-butyllithium; hydroxylamine hydrochloride; diisopropylamine; sodium hydroxide; In tetrahydrofuran; ethanol; hexane; water;