6-AMINOHEXYL-N-ACETYL-B-D-THIOGLUCOSAMIN IDE

Base Information

• Chemical Name: 6-AMINOHEXYL-N-ACETYL-B-D-THIOGLUCOSAMIN IDE
• CAS No.: 51224-17-0
• Molecular Formula: C14H28N2O5S
• Molecular Weight: 335.43958
• Mol file: 51224-17-0.mol

Synonyms:6-AMINOHEXYL-N-ACETYL-B-D-THIOGLUCOSAMIN IDE;6-aminohexyl N-acetyl-beta-D-thioglucosaminide

Chemical Property of 6-AMINOHEXYL-N-ACETYL-B-D-THIOGLUCOSAMIN IDE

Chemical Property:

• PSA: 153.83000
• LogP: 0.72300
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

6-AMINOHEXYL-2-ACETAMIDO-2-DEOXY-1-THIO-BETA-D-GLUCOPYRANOSIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-AMINOHEXYL-N-ACETYL-B-D-THIOGLUCOSAMIN IDE

There total 6 articles about 6-AMINOHEXYL-N-ACETYL-B-D-THIOGLUCOSAMIN IDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-acetylamino-6-[6-(2,2,2-trifluoro-acetylamino)-hexylsulfanyl]-tetrahydro-pyran-4-yl ester (77346-20-4) → N-[(2S,3R,4R,5S,6R)-2-(6-Amino-hexylsulfanyl)-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl]-acetamide (51224-17-0)

Guidance literature:

DOI:10.1016/S0008-6215(00)85209-X

Reference yield:

2-Acetamino-3,4,6-tri-O-acetyl-1,2-bisdesoxy-1-S-isothioureido-β-D-glucopyranose (73982-52-2) → N-[(2S,3R,4R,5S,6R)-2-(6-Amino-hexylsulfanyl)-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl]-acetamide (51224-17-0)

Guidance literature:

Multi-step reaction with 2 steps

1: method in ref. 1

DOI:10.1016/S0008-6215(00)85209-X

Reference yield:

6-amino-1-hexanol (4048-33-3) → N-[(2S,3R,4R,5S,6R)-2-(6-Amino-hexylsulfanyl)-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl]-acetamide (51224-17-0)

Guidance literature:

Multi-step reaction with 4 steps

1: 70 percent / 1.) room temp., 5 h, 2.) 4 deg C

2: method in ref. 1

3: method in ref. 1

DOI:10.1016/S0008-6215(00)85209-X

upstream raw materials:

Acetic acid (2R,3S,4R,5R,6S)-3-acetoxy-2-acetoxymethyl-5-acetylamino-6-[6-(2,2,2-trifluoro-acetylamino)-hexylsulfanyl]-tetrahydro-pyran-4-yl ester

2-Acetamino-3,4,6-tri-O-acetyl-1,2-bisdesoxy-1-S-isothioureido-β-D-glucopyranose

6-amino-1-hexanol

6-trifluoroacetamido-1-hexanol

Refernces